91713-64-3

Basic information

• Product Name: diethyl 2-nitro-4-benzoylphenylmalonate
• Synonyms: diethyl 2-nitro-4-benzoylphenylmalonate
• CAS NO: 91713-64-3
• Molecular Weight: 385.373
• Mol File: 91713-64-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: diethyl 2-nitro-4-benzoylphenylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-nitro-4-benzoylphenylmalonate(91713-64-3)
• EPA Substance Registry System: diethyl 2-nitro-4-benzoylphenylmalonate(91713-64-3)

Safety Data

• Hazardous Substances Data: 91713-64-3(Hazardous Substances Data)

Upstream product

• 56107-02-9 4-chloro-3-nitrobenzophenone 
• 105-53-3 diethyl malonate 
• 56107-03-0 4-bromo-3-nitrobenzophenone 

Downstream Products

• 104019-15-0 2-nitro-4-benzoylphenylacetic acid 
• 91714-68-0 Sodium; (2-amino-4-benzoyl-phenyl)-acetate 
• 215959-32-3 6-Benzoyl-3,3-dibromo-1,3-dihydro-indol-2-one 
• 91713-63-2 6-benzoyloxindole 

Relevant articles and documents

An improved procedure for the regiospecific synthesis of electron deficient 4- and 6-substituted isatins

The regiospecific synthesis of 4- and 6-substituted isatins 5a-g in four steps from halonitrobenzenes 1a-g has been investigated for a variety of substrates (Scheme 1). The procedure makes use of readily available, easily handled materials and in most cases purification of neither intermediates nor final products is required. Yields of isatins are between 26 and 75% (Table 1). Improved yields of known isatins are reported as well as the syntheses of previously unreported isatins. This method, taken together with known procedures, provides for the synthesis of the full complement of isatin regioisomers.

1,3-dicarboxamide-oxindoles as antiinflammatory agents

1,3-Dicarboxamidooxindoles as antiinflammatory agents prepared by reaction of the 1-carbamoyloxindole with an isocyanate or by aminolysis of the corresponding alkyl 1-carbamoyloxindole-3-carboxylate.

Oxindole antiinflammatory agents

Ketone containing 1-substituted oxindole-3-carboxamides as antiinflammatory agents prepared by reaction of the 1-substituted oxindole with an isocyanate or by aminolysis of the corresponding alkyl oxindole-3-carboxylate.