917965-96-9Relevant academic research and scientific papers
C-aminoimidoylation and C-thiocarbamoylation of esters, sulfones, and ketones
Katritzky, Alan R.,Khashab, Niveen M.,Haase, Danniebelle N.,Yoshioka, Megumi,Ghiviriga, Ion,Steel, Peter J.
, p. 6742 - 6748 (2007)
(Chemical Equation Presented) Esters, sulfones, and ketones were C-aminoimidoylated and C-thiocarbamoylated by benzotriazole-1-carboxamidines 8a-g and 1-(alkyl-or-arylthiocarbamoyl)benzotriazoles 9a-i, respectively. The present work represents the first s
SUBSTITUTED PYRR0LIDIN-2-0NES , PIPERIDIN-2-0NES AND ISOTHIAZOLIDINE-1, 1-DIOXIDES, THEIR USE AS KVl .5 POTASSIUM CHANNEL BLOCKERS AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM
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Page/Page column 40, (2010/11/25)
The invention relates to compounds of the formula (I), in which A, R1 , R2, R3, R4, R5, R6, R7 and n have the meanings stated in the claims. The compounds are particularly suitable as antiarrhythmic active ingredients, in particular for the treatment and prophylaxis of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.
