91851-01-3

Upstream product

• 1074-12-0 phenylglyoxal hydrate 
• 106-40-1 4-bromo-aniline 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 

Downstream Products

• 946614-70-6 dimethyl-2-(tert-butylamino)-5-phenyl-3,4-furan dicarboxylate 
• 91851-17-1 2-((4-bromophenyl)amino)-1-phenylethan-1-ol 
• 55282-25-2 N,N'-(benzoylmethylene)di-p-bromoaniline 
• 19027-81-7 N-Phenacyliden-4-brom-anilin 

Relevant academic research and scientific papers

Reaction between isocyanides, dialkyl acetylenedicarboxylates and 2-hydroxy-1-aryl-2-(arylamino)ethanones: One-pot synthesis of highly functionalized 2-aminofurans

A facile synthesis of highly functionalized 2-aminofuran derivatives by the multicomponent reaction of alkyl isocyanides, dialkyl acetylenedicarboxylates and 2-hydroxy-1-aryl-2-(arylamino)ethanone is described. The reaction is characterized by mild condit

The Reaction of Phenylglyoxal with Primary Aliphatic and Aromatic Amines. Synthesis of Phenylglyoxal Monoimines and some Derivatives.

Condensation of phenylglyoxal with primary aliphatic amines yields the related keto-aldimines.When primary aromatic amines are used, aldimines, amino-hydroxy-ketones, diamino-ketones, and alkoxy-amino-ketones are obtained depending upon the nature of the amine and the experimental conditions.Alternatively the monoimines can be obtained by dehydration of C-hydroxyphenacylarylamines and by demethanolation of C-methoxyphenacylarylamines both on treatment with Pd/C catalyst.Reduction of phenylglyoxal monoimines with sodium borohydride yielded H-substituted 1-phenyl-2-aminoethanols and 1,3-dipolar cycloaddition of the imines with p-chlorobenzonitrile oxide afforded 4-substituted 5-benzoyl-3-(p-chlorophenyl)-4,5-dihydro-1,2,4-oxadiazoles.