19027-81-7

Upstream product

• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 106-40-1 4-bromo-aniline 
• 98-86-2 acetophenone 
• 1074-12-0 phenylglyoxal hydrate 
• 91851-01-3 2-(4-Bromo-phenylamino)-2-hydroxy-1-phenyl-ethanone 

Downstream Products

• 131856-83-2 Methyl 4-(p-bromophenyl)imino-3-hydroxy-2,2-dimethyl-3-phenylbutanoate 
• 91851-17-1 2-((4-bromophenyl)amino)-1-phenylethan-1-ol 

Relevant academic research and scientific papers

Reductive Alkylation of α-Keto Imines Catalyzed by PTSA/FeCl3: Synthesis of Indoles and 2,3′-Biindoles

A simple and efficient method for the synthesis of highly functionalized indoles and biindoles was developed. In the reaction protocol, three components were used in one pot and products were obtained in high yield in an easy workup procedure. The reactio

Antifungal activities of ketoazomethines of phenyl glyoxal and p-substituted anilines

A new series of ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) with various p-substituted anilines viz. p-Cl, p-Br, p-NO2, p-(C2H 5)2N and p-CH

Synthesis and antifungal activity of 2-Ketophenyl-3 substituted aryl-1-thiazolidin-4-ones

A new series of 2-ketophenyl-3-substituted aryl-1- thiazolidin-4- ones were synthesized by cyclocondensation of ketoazomethines and thioglycolic acid. Ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of ace

The Reaction of Phenylglyoxal with Primary Aliphatic and Aromatic Amines. Synthesis of Phenylglyoxal Monoimines and some Derivatives.

Condensation of phenylglyoxal with primary aliphatic amines yields the related keto-aldimines.When primary aromatic amines are used, aldimines, amino-hydroxy-ketones, diamino-ketones, and alkoxy-amino-ketones are obtained depending upon the nature of the amine and the experimental conditions.Alternatively the monoimines can be obtained by dehydration of C-hydroxyphenacylarylamines and by demethanolation of C-methoxyphenacylarylamines both on treatment with Pd/C catalyst.Reduction of phenylglyoxal monoimines with sodium borohydride yielded H-substituted 1-phenyl-2-aminoethanols and 1,3-dipolar cycloaddition of the imines with p-chlorobenzonitrile oxide afforded 4-substituted 5-benzoyl-3-(p-chlorophenyl)-4,5-dihydro-1,2,4-oxadiazoles.