918867-78-4

Basic information

• Product Name: Benzamide, N-(1,1-dimethylethyl)-2-(1-methylethenyl)-
• CAS NO: 918867-78-4
• Molecular Formula: C14H19NO
• Molecular Weight: 217.311
• Mol File: 918867-78-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(1,1-dimethylethyl)-2-(1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(1,1-dimethylethyl)-2-(1-methylethenyl)-(918867-78-4)
• EPA Substance Registry System: Benzamide, N-(1,1-dimethylethyl)-2-(1-methylethenyl)-(918867-78-4)

Safety Data

• Hazardous Substances Data: 918867-78-4(Hazardous Substances Data)

Upstream product

• 2438-04-2 2-isopropylbenzoic acid 
• 53881-34-8 2-isopropylbenzoic acid chloride 
• 590-14-7 1-bromo-1-propene 
• 5894-65-5 N-t-butylbenzamide 
• 2039-88-5 2-bromostyrene 
• 57807-28-0 1-bromo-2-cyclopropylbenzene 
• 7073-70-3 1-bromo-2-isopropenylbenzene 
• 1609-86-5 Tert-butyl isocyanate 
• 918867-71-7 N-tert-butyl-2-cyclopropylbenzamide 
• 3158-74-5 2-cyclopropylbenzoic acid 

Relevant articles and documents

Method for synthesizing olefin through selective desaturation of inert carbon-carbon bonds

The invention relates to a method for synthesizing olefin by selective desaturation of inert carbon-carbon bonds. The method comprises the following steps of: synthesizing a chlorinated amide compound serving as a raw material in the presence of visible light, a ruthenium catalyst and a ligand, and post-treating reaction liquid to obtain a remote alkenyl amide compound. In the presence of the ruthenium catalyst and the phenylpyridine ligand, intramolecular carbon-hydrogen bond activation of the amide compound is successfully realized, and the remote olefin compound is synthesized; according to the method, chloro-amide which is simple and easy to obtain is used as a raw material, the substrate application range is wide, and the reaction efficiency is high; in the free radical migration process, 1, 5 migration occurs all the time along with beta-H elimination, terminal alkene and conjugated double bonds are used as main products, and high regioselectivity is achieved; and the maximum E/Z value of the obtained olefin compound is greater than 20: 1, and the stereoselectivity is good. The double bond of the compound can be further converted into other functional groups, the conversion process is simple in one step, and the obtained derivative can be used as a medical intermediate and has high potential application value.

Ortho-directed functionalization of arenes using magnesate bases

Ortho-directed functionalisation of arenes using lithium alkylmagnesate bases were achieved, demonstrating the potential use of arylmagnesates as suitable arylanions, without a further transmetallation step, for challenging functionalizations such as fluorination, hydroxylation, arylation, vinylation and alkylation through epoxide ring-opening.

Palladium-catalyzed oxidative activation of arylcyclopropanes

(Diagram presented) Palladium chloride-catalyzed intramolecular activation of electroneutral cyclopropane derivatives results in cleavage of the cyclopropane ring followed by formation of heterocyclic derivatives. Phenols, carboxylic acids, and amide groups were considered as substituents ortho to the cyclopropane ring in this catalytic activation chemistry. The regioselectivity observed in the case of amide-containing substrates was different from that of carboxylic acid-containing substrates, ruling out simple cyclopropane isomerization followed by a Wacker oxidation as the mechanistic pathway.