3158-74-5

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Cyclopropylbenzoic acid is utilized as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs due to its unique structural properties and potential biological activity.
Used in Agrochemical Production:
2-CYCLOPROPYLBENZOIC ACID also serves as a building block in the production of agrochemicals, playing a vital role in the creation of pesticides and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Compounds Synthesis:
2-Cyclopropylbenzoic acid is employed as a fundamental component in the synthesis of a wide range of organic compounds, showcasing its versatility and importance in organic chemistry.
It is essential to handle and store 2-cyclopropylbenzoic acid with caution due to its potential health and environmental hazards, ensuring proper management to mitigate any risks associated with its use.

Upstream product

• 20034-51-9 2-cyclopropylbenzaldehyde 
• 124-38-9 carbon dioxide 
• 57807-28-0 1-bromo-2-cyclopropylbenzene 
• 2039-88-5 2-bromostyrene 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 148438-01-1 methyl 2-cyclopropylbenzoate 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 892390-51-1 C₁₅H₂₀NO⁽¹⁺⁾*I^(1-) 
• 873-49-4 cyclopropylbenzene 
• 3155-00-8 2-cyclopropylbenzamide 

Downstream Products

• 918867-71-7 N-tert-butyl-2-cyclopropylbenzamide 
• 918867-78-4 N-(tert-butyl)-2-(prop-1-en-2-yl)benzamide 
• 918867-73-9 2-cyclopropyl-N-phenylbenzamide 
• 918867-69-3 N-butyl-2-cyclopropylbenzamide 
• 918867-72-8 N-benzyl-2-cyclopropylbenzamide 
• 918867-70-6 N-(4-chlorophenethyl)-2-cyclopropylbenzamide 
• 73109-01-0 3-methyl-2-phenylisoquinolin-1(2H)-one 
• 53890-83-8 2-phenyl-3,3-dimethylisoindoline-1-one 
• 39774-23-7 1-oxo-3-methyl-2-phenylmethyl-1,2-dihydroisoquinoline 
• 50564-92-6 2-benzyl-3,3-dimethylisoindolin-1-one 
• 918867-74-0 2-cyclopropyl-N-tosylbenzamide 

Relevant academic research and scientific papers

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

DIFLUOROMETHYLENE COMPOUND

The present invention relates to a compound having an URAT1 inhibitory activity, and to an URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition containing the compound. More specifically, the present invention relates to a compound represented by the formula (I): wherein R1 is -Q1-A1 or the like; R2 is a hydrogen atom, a halogen atom, a lower alkyl group or the like; W1, W2, W3 and W4 are each independently a nitrogen atom or a methine group optionally having substituents, or the like; X and Y are each a single bond, an oxygen atom or the like; Z is a hydroxyl group or COOR3 or the like.

Palladium-catalyzed oxidative activation of arylcyclopropanes

(Diagram presented) Palladium chloride-catalyzed intramolecular activation of electroneutral cyclopropane derivatives results in cleavage of the cyclopropane ring followed by formation of heterocyclic derivatives. Phenols, carboxylic acids, and amide groups were considered as substituents ortho to the cyclopropane ring in this catalytic activation chemistry. The regioselectivity observed in the case of amide-containing substrates was different from that of carboxylic acid-containing substrates, ruling out simple cyclopropane isomerization followed by a Wacker oxidation as the mechanistic pathway.

NOVEL COMPOUNDS

A compound of Formula (I) and pharmaceutically and/or veterinarily acceptable derivatives thereof, wherein: R1 is H, C1-6alkyl, - C(A)D, C3-8cycloalkyl, aryl, het, aryl-C1-4alkyl or het-C1-4/sub

2-Cyclopropylbenzoic acids in the synthesis of phthalides and 3,4-dihydroisocoumarins

2-Cyclopropylbenzoic acids, under the action of strong protic acids (FSO3H, H2SO4), are convened to 3-ethylphthalidium ions. In solutions in these inorganic acids, the 3-ethylphthalidium ions are isomerized to 3-methyl-3,4