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918892-30-5

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  • SAGECHEM/ (4-Chlorophenyl)(isocyano)methyl 4-methylphenyl sulfone /Manufacturer in China

    Cas No: 918892-30-5

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918892-30-5 Usage

General Description

A-Tosyl-(4-chlorobenzyl) isocyanide is a chemical compound with the molecular formula C15H13ClN2O2S. It is a tosyl-protected isocyanide derivative that is commonly used in organic synthesis as a versatile building block for the preparation of various functionalized compounds. A-Tosyl-(4-chlorobenzyl) isocyanide is known for its reactivity towards a wide range of nucleophiles, making it a valuable tool in the development of new synthetic methodologies. It is also used as a precursor in the synthesis of pharmaceuticals and other biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 918892-30-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,8,9 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 918892-30:
(8*9)+(7*1)+(6*8)+(5*8)+(4*9)+(3*2)+(2*3)+(1*0)=215
215 % 10 = 5
So 918892-30-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H12ClNO2S/c1-11-3-9-14(10-4-11)20(18,19)15(17-2)12-5-7-13(16)8-6-12/h3-10,15H,1H3

918892-30-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(4-chlorophenyl)-isocyanomethyl]sulfonyl-4-methylbenzene

1.2 Other means of identification

Product number -
Other names (4-Chlorophenyl)(isocyano)methyl 4-methylphenyl sulphone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:918892-30-5 SDS

918892-30-5Relevant articles and documents

A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

Aihara, Hideki,Cui, Huarui,Divakaran, Anand,Ellingson, Mikael O.,Gee, Clifford T.,Griffith, Elizabeth C.,Harki, Daniel A.,Hoell, Zachariah J.,Johnson, Jorden A.,Khanal, Shalil,Lee, Amani L.,Lee, Richard E.,Pomerantz, William C. K.,Scholtz, Cole R.,Shah, Vijay H.,Shi, Ke,Zahid, Huda

supporting information, (2022/01/27)

Chemical probes for epigenetic proteins are essential tools for dissecting the molecular mechanisms for gene regulation and therapeutic development. The bromodomain and extra-terminal (BET) proteins are master transcriptional regulators. Despite promising

The base-free van Leusen reaction of cyclic imines on water: Synthesis of N-fused imidazo 6,11-dihydro β-carboline derivatives

Satyam, Killari,Murugesh,Suresh, Surisetti

supporting information, p. 5234 - 5238 (2019/06/07)

Construction of imidazoles has been demonstrated on water under base-free conditions. The reaction of dihydro β-carboline imines and p-toluenesulfonylmethyl isocyanides furnished the corresponding substituted N-fused imidazo 6,11-dihydro β-carboline derivatives in very good yields under ambient conditions. The use of deuterium oxide (D2O) as a solvent enabled the incorporation of deuterium isotopes in the imidazole ring.

LXR MODULATORS

-

Page/Page column 168, (2014/09/29)

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.

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