91944-99-9

Usage

Uses

Used in Pharmaceutical Industry:
Benzonitrile, 4-[(6-bromohexyl)oxy]is used as an intermediate in the synthesis of Ethyl 4-[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzimidoate (E900958), which is an impurity of Hexamidine Diisetionate (H294205). Hexamidine Diisetionate is an amidine compound employed in the treatment of amyloid-related diseases, making Benzonitrile, 4-[(6-bromohexyl)oxy]a crucial component in the development of therapeutic agents for such conditions.
Used in Cosmetics Industry:
Benzonitrile, 4-[(6-bromohexyl)oxy]is used as a preservative in cosmetics, serving as an antiseptic. Its inclusion in cosmetic products helps maintain their quality and safety by preventing the growth of harmful microorganisms, thereby ensuring the well-being of consumers.

Upstream product

• 629-03-8 1 ,6-dibromohexane 
• 767-00-0 4-cyanophenol 

Downstream Products

• 91945-32-3 1-(4-{[7-(3-methyl-5-isoxazolyl)heptyl]oxy}phenyl)ethanone 
• 91945-23-2 5-[7-(4-ethoxycarbonylphenoxy)heptyl]-3-methylisoxazole 
• 91945-35-6 3-methyl-5-[7-(4-carboxamidophenoxy)heptyl]isoxazole 
• 91945-17-4 4-<<7-(3-methyl-5-isoxazolyl)heptyl>oxy>benzoic acid 
• 854895-32-2 2-(4-(6-(4-cyanophenoxy)hexyloxy)phenyl)benzofuran-5-carbonitrile 

Relevant academic research and scientific papers

NARROW ABSORPTION POLYMER NANOPARTICLES AND RELATED METHODS

Polymers, monomers, narrow-band absorbing polymers, narrow-band absorbing monomers, absorbing units, polymer dots, and related methods are provided. Bright, luminescent polymer nanoparticles with narrow-band absorptions are provided. Methods for synthesizing absorbing monomers, methods for synthesizing the polymers, preparation methods for forming the polymer nanoparticles, and applications for using the polymer nanoparticles are also provided.

AMIDINE SUBSTITUTED ANALOGUES AND USES THEREOF

The present application relates to amidine substituted analogues as shown in formula I and uses thereof as an anti-inflammatory agent and/or for the treatment of an immunological disorder or of an inflammatory bowel disease including ulcerative colitis, C

gem-Dithioacetylated indole derivatives as novel antileishmanial agents

In this communication we report a serendipitously discovered hybrid molecule 1, combining fragment of 3 (an in vivo active antileishmanial molecule) with H2S donor moiety (known for bimodal behavior of cytoprotection and apoptosis), as antileis

Liquid crystalline dihydroazulene photoswitches

A large selection of photochromic dihydroazulene (DHA) molecules incorporating various substituents at position 2 of the DHA core was prepared and investigated for their ability to form liquid crystalline phases. Incorporation of an octyloxy-substituted b

Copper-catalyzed/promoted cross-coupling of gem -diborylalkanes with nonactivated primary Alkyl halides: An alternative route to alkylboronic esters

The first copper-catalyzed/promoted sp3-C Suzuki-Miyaura coupling reaction of gem-diborylalkanes with nonactivated electrophilic reagents is reported. Not only 1, 1-diborylalkanes but also some other gem-diborylalkanes can be coupled with nonactivated primary alkyl halides, offering a new method for sp3C-sp3C bond formation and, simultaneously, providing a new strategy for the synthesis of alkylboronic esters.

Nickel-catalyzed sonogashira reactions of non-activated secondary alkyl bromides and iodides

A nicked reaction: The title reaction of terminal alkynes with non-activated secondary alkyl iodides and bromides was accomplished for the first time. This reaction provides a new and practical approach for the synthesis of substituted alkynes (see scheme; cod=cyclo-1,5-octadiene). Copyright

Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif

Forty-eight cationically substituted pentamidine congeners possessing benzofuran rings were synthesized by a copper mediated heteroannulation of substituted o-iodophenols with phenyl acetylenes. Activities of compounds 1-48 against Trypanosoma brucei rhod

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.

Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents

Compounds of the formula STR1 wherein: Y is an alkylene bridge of 3-9 carbon atoms; Z is N or HC; R is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when Z is N, R is lower-alkyl; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and Het is selected from specified heterocyclic groups, are useful and antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.

[[(4,5-Dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles. Inhibitors of picornavirus uncoating

A series of [[(4,5-dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles has been synthesized and evaluated as antipicornavirus agents. The effect of alkyl groups in the 4- and 5-position of the oxazoline ring, as well as the alkyl chain length, on antiviral activi