87495-31-6

Basic information

• Product Name: Disoxaril
• Synonyms: Disoxaril;3-Methyl-5-[7-[4-(2-oxazolin-2-yl)phenoxy]heptyl]isoxazole;5-[7-[4-(4,5-Dihydrooxazol-2-yl)phenoxy]heptyl]-3-methylisoxazole;Win-51711
• CAS NO: 87495-31-6
• Molecular Formula: C₂₀H₂₆N₂O₃
• Molecular Weight: 342.432
• Mol File: 87495-31-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 522.1°Cat760mmHg
• Flash Point: 269.6°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 1.77E-10mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: Disoxaril(CAS DataBase Reference)
• NIST Chemistry Reference: Disoxaril(87495-31-6)
• EPA Substance Registry System: Disoxaril(87495-31-6)

Safety Data

• Hazardous Substances Data: 87495-31-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 87495-31-6 differently. You can refer to the following data:
1. .Antiviral.
2. Disoxaril is used as an anti-viral against human rhinovirus.

InChI:InChI=1/C20H26N2O3/c1-16-15-19(25-22-16)7-5-3-2-4-6-13-23-18-10-8-17(9-11-18)20-21-12-14-24-20/h8-11,15H,2-7,12-14H2,1H3

Upstream product

• 81428-58-2 4-(4,5-dihydro-2-oxazolyl)phenol 
• 91945-38-9 7-(3-methylisoxazol-5-yl)heptyl bromide 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 93472-62-9 4,5-dihydro-2-(4-hydroxyphenyl)oxazole hydrochloride 
• 91944-98-8 ethyl 4-<<7-(3-methyl-5-isoxazolyl)heptyl>oxy>benzonitrile 
• 767-00-0 4-cyanophenol 
• 91944-99-9 4-<(6-bromohexyl)-oxy>benzonitrile 
• 629-03-8 1 ,6-dibromohexane 

Relevant articles and documents

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.

[[(4,5-Dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles. Inhibitors of picornavirus uncoating

A series of [[(4,5-dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles has been synthesized and evaluated as antipicornavirus agents. The effect of alkyl groups in the 4- and 5-position of the oxazoline ring, as well as the alkyl chain length, on antiviral activi