98360-44-2Relevant academic research and scientific papers
Enantiomeric effects of homologues of disoxaril on the inhibitory activity against human rhinovirus-14
Diana,Otto,Treasurywala,McKinlay,Oglesby,Maliski,Rossmann,Smith
, p. 540 - 544 (1988)
X-ray crystallography studies of racemic 5-[7-[4-(4,5-dihydro-4-methyl-2-oxazolyl)phenoxy]heptyl]-3-methyl isoxazole (2) bound to human rhinovirus-14 (HRV-14) indicate selective binding of the S isomer. This result correlates well with the 10-fold greater
[[(4,5-Dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles. Inhibitors of picornavirus uncoating
Diana,McKinlay,Otto,Akullian,Oglesby
, p. 1906 - 1910 (2007/10/02)
A series of [[(4,5-dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles has been synthesized and evaluated as antipicornavirus agents. The effect of alkyl groups in the 4- and 5-position of the oxazoline ring, as well as the alkyl chain length, on antiviral activi
