919764-04-8

Basic information

• Product Name: Propanoic acid, 2,2-dimethyl-, 3-[4-hydroxy-3-methoxy-5-(2-propen-1-yl)phenyl]propyl ester
• CAS NO: 919764-04-8
• Molecular Formula: C18H26O4
• Molecular Weight: 306.402
• Mol File: 919764-04-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2,2-dimethyl-, 3-[4-hydroxy-3-methoxy-5-(2-propen-1-yl)phenyl]propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2,2-dimethyl-, 3-[4-hydroxy-3-methoxy-5-(2-propen-1-yl)phenyl]propyl ester(919764-04-8)
• EPA Substance Registry System: Propanoic acid, 2,2-dimethyl-, 3-[4-hydroxy-3-methoxy-5-(2-propen-1-yl)phenyl]propyl ester(919764-04-8)

Safety Data

• Hazardous Substances Data: 919764-04-8(Hazardous Substances Data)

Upstream product

• 854664-22-5 2-allyl-4-(3-hydroxypropyl)-6-methoxyphenol 
• 3282-30-2 pivaloyl chloride 
• 97-53-0 4-allylguaiacol 
• 2305-13-7 3-Guaiacylpropanol 
• 919764-03-7 allyl 2-methoxy-4-(3-pivaloyloxypropyl)phenyl ether 
• 130447-88-0 3-(4-(allyloxy)-3-methoxyphenyl)propan-1-ol 

Downstream Products

• 919764-07-1 [2-methoxy-4-(3-pivaloyloxypropyl)-6-(2-propenyl)phenyl](3,4,5-trimethoxybenzyl) ether 
• 919764-09-3 [2-methoxy-6-(methoxycarbonylmethyl)-4-(3-pivaloyloxypropyl)phenyl][3,4-di(pivaloyloxy)benzyl] ether 
• 919764-10-6 [2-methoxy-6-(methoxycarbonylmethyl)-4-(3-pivaloyloxypropyl)phenyl](3,4,5-trimethoxybenzyl) ether 
• 919764-06-0 [2-methoxy-4-(3-pivaloyloxypropyl)-6-(2-propenyl)phenyl][3,4-di(pivaloyloxy)benzyl] ether 

Relevant articles and documents

A diastereoselective route to trans-2-aryl-2,3-dihydrobenzofurans through sequential cross-metathesis/isomerization/allylboration reactions: Synthesis of bioactive neolignans

A new highly diastereoselective synthetic route to trans-2,3-dihydrobenzofuran systems, in particular those bearing an aryl substituent at the C2 position, is described. The cornerstone of our strategy is the implementation of a cross-metathesis/isomerization/allylboration sequence starting from 2-allyl-substituted phenols and aldehydes. After an intramolecular Mitsunobu cyclization step, the anti-homoallylic alcohols allow the synthesis of the desired skeleton in a stereoselective fashion. As an illustration, we used this strategy for the preparation of the dihydrodehydrodiconiferyl alcohol (1a), a natural dihydrobenzofuran neolignan, as well as for a formal synthesis of its O-demethylated derivative 1b. An enantioselective version of this approach employing a chiral phosphoric acid in the allylboration step is also studied.