92016-16-5

Upstream product

• 29941-87-5 isobutyl enol ether of cyclohexane-1,2-dione 
• 105-36-2 ethyl bromoacetate 
• 220033-61-4 2,2-Bis-p-tolylsulfanyl-cyclohexanone 
• 220033-62-5 (1-Hydroxy-2,2-bis-p-tolylsulfanyl-cyclohexyl)-acetic acid ethyl ester 

Downstream Products

• 90200-01-4 2-(1-hydroxy-2-oxocyclohexyl)acetic acid 
• 75032-20-1 (1-Hydroxy-2-oxocyclohexyl)essigsaeure-methylester 
• 90534-64-8 methyl 2-(6-oxocyclohex-1-en-1-yl)acetate 
• 1438-96-6 (2-oxocyclohexyl)acetic acid 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure (R)- and (S)-2-ethoxycarbonylmethyl- 2-hydroxy-cyclohexanones

Sulfenylation of 2-p-tolylsulfinyl cyclohexanone can be achieved at - 78°C with thiosulfonates. The in situ aldol reaction of these compounds with ethyl acetate enolate is highly stereoselective (1,2-asymmetric induction) and yields diastereomeric mixture