921630-61-7

Basic information

• Product Name: Benzaldehyde, 4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-
• CAS NO: 921630-61-7
• Molecular Formula: C16H14Cl2O3
• Molecular Weight: 325.191
• Mol File: 921630-61-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-(921630-61-7)
• EPA Substance Registry System: Benzaldehyde, 4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-(921630-61-7)

Safety Data

• Hazardous Substances Data: 921630-61-7(Hazardous Substances Data)

Upstream product

• 2432-12-4 2,6-dichloro-4-methylophenol 
• 877995-77-2 1-(4-bromophenoxy)-2-(2,6-dichloro-4-methylphenoxy)ethane 
• 201230-82-2 carbon monoxide 
• 68-12-2 N,N-dimethyl-formamide 
• 921630-64-0 2-(2,6-dichloro-4-methyl-phenoxy)-ethanol 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 1251530-37-6 C₂₀H₂₀Cl₂O₄ 
• 1026192-65-3 sodium 2-{[3-{[(3-amino-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}propanoyl)(cyclopropyl)amino]methyl}-5-(3-methoxypropyl)phenoxy]methyl}cyclopropanecarboxylate 
• 1056555-28-2 ethyl 2-(((3-(((3-(tert-butoxycarbonyl)amino)-2-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)benzyl)propanoyl)(cyclopropyl)amino)methyl)-5-(3-methoxypropyl)phenoxy)methyl)cyclopropanecarboxylate 
• 1056555-23-7 tert-butyl (3-[(cyclopropyl)[3-(3-methoxypropyl)-5-(2-pyrrolidin-1-ylethoxy)benzyl]amino]-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 1056555-32-8 tert-butyl (3-(cyclopropyl((2-(3-methoxypropyl)-6-(3-(methylsulfonyl)propoxy)-1-oxidopyridin-4-yl)methyl)amino)-2-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)benzyl)-3-oxopropyl)carbamate 
• 1056555-25-9 tert-butyl (3-[(cyclopropyl)[3-(3-methoxypropyl)-5-[3-(methylsulfonyl)propoxy]benzyl]amino]-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 1056555-30-6 tert-butyl (3-(cyclopropyl((2-(3-methoxypropyl)-6-(3-(methylsulfonyl)propoxy)pyridin-4-yl)methyl)amino)-2-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)benzyl)-3-oxopropyl)carbamate 
• 1056555-22-6 tert-butyl (3-[[3-{[tert-butyl(dimethyl)silyl]oxy}-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 1056555-31-7 tert-butyl (3-[{[2-{[tert-butyl(dimethyl)silyl]oxy}-6-(3-methoxypropyl)pyridin-4-yl]methyl}(cyclopropyl)amino]-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 1056555-26-0 tert-butyl (3-{cyclopropyl[3-(3-methoxypropyl)-5-(2-pyridin-2-ylethoxy)benzyl]amino}-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 1056555-24-8 tert-butyl (3-[(cyclopropyl)[3-(3-methoxypropyl)-5-[3-(methylthio)propoxy]benzyl]amino]-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-3-oxopropyl)carbamate 
• 921629-96-1 3-{[(3-amino-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}propanoyl)(cyclopropyl)amino]methyl}-5-(3-methoxypropyl)phenyl (3-amino-2,2-dimethyl-3-oxopropyl)carbamate 
• 921629-56-3 3-amino-N-cyclopropyl-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-N-[3-(3-methoxypropyl)-5-(2-pyrrolidin-1-ylethoxy)benzyl]propanamide 
• 921629-90-5 3-amino-N-cyclopropyl-2-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl}-N-({2-(3-methoxypropyl)-6-[3-(methylsulfonyl)propoxy]-1-oxidopyridin-4-yl}methyl)propanamide 

Relevant articles and documents

Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study

Time-dependent inhibitors of CYPs have the potential to perpetrate drug-drug interactions in the clinical setting. After finding that several leading compounds in a novel series of substituted amino propanamide renin inhibitors inactivated CYP3A4 in an NA

RENIN INHIBITORS

The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as wel

RENIN INHIBITORS

The present invention relates to novel renin inhibitors of the general Formula (I), and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds. These novel renin inhibitors are used in treating cardiovascular events and renal insufficiency.