92222-40-7

Upstream product

• 591-50-4 iodobenzene 
• 4114-31-2 ethylhydrazine carboxylate 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 588-64-7 benzaldehyde phenylhydrazone 
• 111709-02-5 benzaldehyde N-(carboethoxy)-N-phenylhydrazone 
• 7664-93-9 sulfuric acid 
• 111709-02-5 ethyl 3-benzylidene-2-phenylcarbazate 
• 541-41-3 chloroformic acid ethyl ester 
• 100-63-0 phenylhydrazine 

Downstream Products

• 1189797-91-8 ethyl 2-[6-methyl-2-(methylthio)quinazolin-4(H)-ylidene]-1-phenylhydrazinecarboxylate 
• 1189797-85-0 9-bromo-2-phenyl-5-(methylsulfanyl)[1,2,4]triazolo[4,3-c]-quinazolin-3(2H)-one 
• 1189797-88-3 9-methyl-5-(methylthio)-2-phenyl[1,2,4]triazolo[4,3-c]-quinazolin-3(2H)-one 
• 28740-63-8 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one 
• 1264670-20-3 (2-tert-butyl-indol-1-yl)phenylcarbamic acid ethyl ester 
• 1264670-19-0 (2-pentyl-indol-1-yl)phenylcarbamic acid ethyl ester 
• 1072190-50-1 phenyl-(2-phenyl-indol-1-yl)carbamic acid ethyl ester 
• 1264670-18-9 phenyl[2-(4-trifluoromethylphenyl)indol-1-yl]carbamic acid ethyl ester 
• 52353-62-5 4-anilino-1-phenyl-1,2,4-triazolidine-3,5-dione 
• 6942-46-7 1-phenylurazole 
• 381730-59-2 3,5-diphenyl-6-(4-nitrophenoxy)-3,6-dihydro-1-oxa-3,4-diazine-2-thione 
• 381730-38-7 3,5-diphenyl-6-(4-nitrophenoxy)-3,6-dihydro-1-oxa-3,4-diazin-2-one 
• 381730-37-6 6-(2-chloro-phenoxy)-3,5-diphenyl-3,6-dihydro-[1,3,4]oxadiazin-2-one 
• 381730-35-4 3,5-diphenyl-6-o-tolyloxy-3,6-dihydro-[1,3,4]oxadiazin-2-one 

Relevant academic research and scientific papers

Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABAA receptors

Based on a pharmacophore model of the benzodiazepine-binding site of GABAA receptors, a series of 2-aryl-2,6-dihydro[1,2,4]triazolo[4,3-c] quinazoline-3,5-diones (structure type I) were designed, synthesized, and identified as high-affinity lig

GABAA RECEPTOR MODULATORS

the resent invention relates to novel compounds of the general formula (I) having anxiolytic, anticonvulsant, sedative-hypnotic and myorelaxant conditions as well as anxiogenic, somnolytic and convulsant conditions in mammals, including humans, as GABAA receptor modulator.

New heterocyclic precursors for thermal generation of reactive, electron-rich 1,2-diaza-1,3-butadienes

Figure presented The preparation and thermolysis of new stable heterocyclic precursors of 1,2-diaza-1,3-butadienes is described. The resulting reactive diazadienes are trapped in situ with N-phenyldiazamaleimide. The effect of precursor structure on the temperature at which the diazadienes are generated is discussed.