92285-33-1Relevant academic research and scientific papers
[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 4. Substituted 6,7-dichloro-2,3-dihydrobenzofurans derived by ring annelation.
Lee,Parks,Bunnell,Plattner,Field,Giebisch
, p. 589 - 594 (2007/10/02)
Ring annelation of the [(aminomethyl)aryloxy]acetic acids produced a series of substituted 6,7-dichloro-2,3-dihydrobenzofuran-2-carboxylic acids. Pharmacologic evaluation of these compounds in rats and dogs indicated that several congeners are extremely p
acetic Acid Esters. A New Class of High-Ceiling Diuretics. 2. Modifications of the Oxyacetic Side Chain
Plattner, Jacob J.,Fung, Anthony K.L.,Smital, Jill R.,Lee, Cheuk-Man,Crowley, Steven R.,et al.
, p. 1587 - 1596 (2007/10/02)
The discovery of high-ceiling natriuretic activity from a series of aminomethyl derivatives of ethyl acetate prompted our continued investigation of this new class of (aryloxy)acetic acid diuretics.Systematic alte
5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
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, (2008/06/13)
Described are compounds of the formula STR1 wherein R1 and R2 independently of one another denote hydrogen or loweralkyl; A is CO, CH2, O, S, SO or CHOH; X is hydrogen, halo, loweralkyl, or --CH2 NR1
