92344-45-1

Upstream product

• 20431-81-6 rac-trans-2-methylamino-cyclohexanol 
• 38898-70-3 cis-2-amino-cyclohexanol-⁽¹⁾ 
• 80-48-8 methyl p-toluene sulfonate 
• 6628-80-4 trans-2-chlorocyclohexanol 

Downstream Products

• 90227-79-5 cis-(2-Hydroxy-cyclohexyl)-methyl-aminomethan-sulfonsaeure 
• 116203-82-8 N-nitrosomethyl-N-2-oxocyclohexylamine 
• 882409-15-6 (1R,2S)-cis-2-(N-methyl)amino-1-cyclohexanol 
• 112708-89-1 (1S,2R)-cis-2-(N-methyl)amino-1-cyclohexanol 
• 853953-23-8 (1R,2R)-2-methylamino-cyclohexanol (R)-mandelic acid salt 
• 137858-60-7 2-(N-t-butyloxycarbonyl-N-methylamino)cyclohexanone 
• 126807-03-2 (4aR,8aR)-2-Isopropoxy-4-methyl-2-phenyl-octahydro-benzo[1,4]oxazine; hydrobromide 
• 126807-02-1 (4aR,8aR)-4-Methyl-2-phenyl-2-propoxy-octahydro-benzo[1,4]oxazine; hydrobromide 
• 126807-01-0 (4aR,8aR)-4-Methyl-2-phenyl-octahydro-benzo[1,4]oxazin-2-ol; hydrochloride 
• 479483-55-1 2-biphenyl-4-yl-4-methyl-octahydro-benzo[1,4]oxazin-2-ol 

Relevant academic research and scientific papers

Protecting group for synthesizing oligonucleotide analogs

Nucleoside analog phosphoramidites are provided in which the 3''-hydroxyl group is protected with an 2-N-amidoethyl group. The 2-N-amidoethyl protected nucleoside analogs are useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with the protected phosphoramidites in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl group can be removed easily under standard conditions.