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Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-(2-methylphenyl)cycloheptene is utilized as a building block in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the creation of a wide range of compounds with potential therapeutic and pesticidal properties.
Used in Flavor and Fragrance Industry:
1-(2-methylphenyl)cycloheptene also serves as an intermediate in the production of flavor and fragrance compounds. Its ability to contribute to the development of new and improved scents for the industry makes it a valuable asset in this field.
Used in Material Science and Chemical Research:
1-(2-methylphenyl)cycloheptene's moderate to low acute toxicity and its structural characteristics make it a promising candidate for further research and development in material science and chemical research. Its potential applications in these areas could lead to the discovery of new materials and chemical processes.

Upstream product

• 13294-30-9 1-chlorocycloheptene 
• 68971-87-9 (2-tolyl)tributyltin 
• 628-92-2 Cycloheptene 
• 66107-34-4 2-methylphenyl triflate 
• 95-48-7 ortho-cresol 
• 95-46-5 2-methylphenyl bromide 
• 287944-13-2 2-(cyclohept-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1147123-27-0 cyclohept-1-enyl diphenyl phosphate 
• 33872-80-9 o-tolyl magnesium chloride 
• 932-31-0 ortho-tolylmagnesium bromide 
• 502-42-1 cycloheptanone 
• 1179645-58-9 C₁₄H₂₀O 

Downstream Products

• 1601312-23-5 6-bromo-1-(o-tolyl)cycloheptene 
• 92298-87-8 (2-methylphenyl)cycloheptane 

Relevant academic research and scientific papers

Auto de-bromine-coupling reactions of 1-aryl-7-bromocycloheptenes

Auto de-bromine-coupling reactions of 1-aryl-7-bromocycloheptenes to a new series of [7-6-6] tricyclic system were described. A variety of substituents at the para-position of the phenyl were amenable to this transformation, including electron-donating groups and halides. The presence of electron-donating groups resulted in a more efficient reaction, with higher yields than the case of halides.

A highly active and general catalyst for the stille coupling reaction of unreactive aryl, heteroaryl, and vinyl chlorides under mild conditions

A β-diketiminatophosphane-palladium complex was found to act as an efficient and general catalyst in the Stille coupling reaction of various aryl and heteroaryl chlorides with organostannanes. The results show that this catalytic system allows for the use of less reactive substrates such as deactivated or sterically hindered aryl chlorides. A catalyst loading of 0.5 mol% was sufficient to achieve excellent performance under relatively mild reaction conditions. Furthermore, the scope of catalyst was extended to the coupling of vinyl chlorides. Copyright

Achieving vinylic selectivity in Mizoroki-heck reaction of cyclic olefins

In Heck reactions of cyclic olefins, the products usually have aryl groups that end up at the allylic and/or homoallylic position. We herein report new selectivity that adds aryl groups to the vinylic position. Cyclic olefins of various ring size worked well. The desired isomers were produced by palladium-hydride-catalyzed isomerization of the initial products. Thus, a specific catalyst must be used so that it can perform two jobs under one set of reaction conditions. Copyright

Rhodium-catalyzed dehydrogenative borylation of cyclic alkenes

A rhodium-catalyzed dehydrogenative borylation of cyclic alkenes is described. This reaction provides direct access to cyclic 1-alkenylboronic acid pinacol esters, useful intermediates in organic synthesis. Suzuki-Miyaura cross-coupling applications are also presented. The Royal Society of Chemistry 2010.

A ligand free and room temperature protocol for Pd-catalyzed kumada-corriu couplings of unactivated alkenyl phosphates

Kumada - Corriu cross-couplings of nonactivated cyclic and acyclic vinyl phosphates with aryl magnesium reagents afforded a series of 1,1-disubtituted alkenes in good yields for most cases when the reactions were performed at room temperature with the sim