92435-56-8

Basic information

• Product Name: 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone
• Synonyms: 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone
• CAS NO: 92435-56-8
• Molecular Formula: C₁₅H₁₃ClO₂
• Molecular Weight: 260.71552
• Mol File: 92435-56-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone(92435-56-8)
• EPA Substance Registry System: 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone(92435-56-8)

Safety Data

• Hazardous Substances Data: 92435-56-8(Hazardous Substances Data)

Usage

General Description

1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone is a chemical compound with a complex structure. It is a ketone compound consisting of a benzene ring with a chlorine atom and another benzene ring with a methoxy group attached to it, connected by a two-carbon chain. 1-(4-Chlorophenyl)-2-(4-Methoxyphenyl)ethanone is commonly used in organic and medicinal chemistry as a building block for the synthesis of various pharmaceuticals and fine chemicals. It possesses potential biological and pharmacological activities, making it valuable for research and development in the pharmaceutical industry. Additionally, it is also used as a reagent in organic synthesis and as an intermediate in the production of various chemicals.

Upstream product

• 6343-93-7 2-(4-methoxyphenyl)acetamide 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 97723-29-0 4-chloro-4'-methoxy-benzoin 
• 108-90-7 chlorobenzene 
• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 193486-29-2 1-(4-chlorophenyl)-3-(4-methoxyphenyl)-2,2-dimethyl-propane-1,3-dione 

Downstream Products

• 1041810-99-4 (Z)-3-chloro-3-(4-chlorophenyl)-2-(4-methoxyphenyl)propenal 
• 54945-17-4 1-(4-chlorophenyl)-2-(4-methoxyphenyl)-ethane-1,2-dione 
• 97723-29-0 4-chloro-4'-methoxy-benzoin 
• 13628-99-4 α-bromo-4-chloro-4'-methoxy-deoxybenzoin 

Relevant articles and documents

Lewis Acid Assisted Electrophilic Fluorine-Catalyzed Pinacol Rearrangement of Hydrobenzoin Substrates: One-Pot Synthesis of (±)-Latifine and (±)-Cherylline

A microwave-irradiated solvent-free pinacol rearrangement of hydrobenzoin substrates catalyzed by a combination of N-fluorobenzenesulfonimide and FeCl3·6H2O was developed. Its selectivity was first investigated by density functional theory (DFT) calculations. Then the functional group tolerance was examined by synthesizing a series of substrates designed based on the insight provided by the DFT calculations. The application of the methodology was demonstrated by the efficient one-pot synthesis of (±)-latifine and (±)-cherylline, both are 4-aryltetrahydroisoquinoline alkaloids isolated from Amaryllidacecae plants.

UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES

This invention relates to a pharmaceutical comprising, as an active ingredient, a ureide derivative represented by formula: or a pharmaceutically acceptable salt thereof. The ureide derivative or a pharmaceutically acceptable salt thereof according to the present invention is useful for relieving pain and treating or preventing neuropathic pain.

Behavior of benzoins and hydroxy ketones in acid media: I. Reaction of 1-aryl-2-(2,5-dimethylthiophen-3-yl)-2-hydroxyethanones with thiols in trifluoroacetic acid

Reactions of 1-aryl-2-(2,5-dimethylthiophen-3-yl)-2-hydroxyethanones with thiols in trifluoroacetic acid lead to formation of substituted 1-aryl-2-(2,5-dimethylthiophen-3-yl)-2-sulfanylethanones. 2005 Pleiades Publishing, Inc.