924632-93-9Relevant academic research and scientific papers
Straightforward synthesis of quinolines from enones and 2-aminobenzyl alcohols using an iridium-catalyzed transfer hydrogenative strategy
Xiong, Biao,Wang, Yingying,Liu, Yuan,Bao, Yandan,Liu, Zhaoguo,Zhang, Yanan,Ling, Yong
, p. 5707 - 5711 (2018/08/17)
A new protocol for the direct synthesis of quinolines from enones and 2-aminobenzyl alcohols via iridium-catalyzed transfer hydrogenative reactions has been demonstrated. This method employs easily available [IrCp?Cl2]2/t-BuOK as the efficient catalyst system, proceeding with the merits of high step- and atom efficiency, mild reaction conditions and operational simplicity. The experimental studies suggest that the reactions start with transfer hydrogenation, followed by the Friedl?nder reaction to give the final products.
Palladium-Based Nanocatalyst for One-Pot Synthesis of Polysubstituted Quinolines
Chen, Benjamin Wei Jie,Chng, Leng Leng,Yang, Jun,Wei, Yifeng,Yang, Jinhua,Ying, Jackie Y.
, p. 277 - 283 (2013/03/13)
The synthesis of quinolines has been achieved through a one-pot, two-step tandem reaction catalyzed with Ag-Pd alloy nanoparticles supported on carbon. Ag-Pd alloy nanoparticles catalyzed the coupling of a ketone with a primary alcohol through a hydrogen autotransfer process, which yields α-alkylated ketones under an Ar flow. These are reacted with 2-aminobenzyl alcohols in a modified Friedlaender synthesis to give polysubstituted quinolines in moderate to good yields.
ANTIBACTERIAL QUINOLINE DERIVATIVES
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Page/Page column 34, (2010/11/25)
The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or Formula (Ib): the pharmaceutically acceptable acid or base addition salts thereof, the quaternary amines thereof, the stereochemically isomer
