925463-70-3

Upstream product

• 925463-61-2 N-(2-benzyloxy-4-hydroxy-8-methyl-5,8-dihydro-naphthalen-1-yl)-4-methyl-benzenesulfonamide 
• 925463-73-6 3-[7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-2-hydroxy-propionitrile 
• 925463-64-5 3-[7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-2-methoxymethoxy-propionitrile 
• 129464-01-3 2-(benzyloxy)-4-fluoro-1-nitrobenzene 
• 100-39-0 benzyl bromide 
• 446-36-6 5-fluoro-2-nitrophenol 
• 925463-63-4 [7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-acetaldehyde 
• 925463-62-3 N-(2-benzyloxy-8-methyl-4-triisopropylsilanyloxy-5,8-dihydro-naphthalen-1-yl)-4-methyl-benzenesulfonamide 
• 925463-44-1 N-(2-benzyloxy-4-hydroxy-phenyl)-4-methyl-benzenesulfonamide 
• 221615-94-7 3-(benzyloxy)-4-nitrophenol 
• 925463-43-0 4-amino-3-benzyloxy-phenol 
• 118618-61-4 1-methyl-1H-indole-2-carbonyl chloride 

Downstream Products

• 925463-71-4 trifluoro-methanesulfonic acid 7-benzyloxy-4-{2-methoxymethoxy-3-[(1-methyl-1H-indole-2-carbonyl)-amino]-propyl}-3-methyl-1-(toluene-4-sulfonyl)-1H-indol-5-yl ester 

Relevant academic research and scientific papers

Aryl amidation routes to dihydropyrrolo[3,2-e]indoles and pyrrolo[3,2-f]tetrahydroquinolines: Total synthesis of the (±)-CC-1065 CPI subunit

CC-1065 and the related duocarmycins are members of a structurally unique family of naturally occurring molecules and remain some of the most rigorously studied antitumor compounds to date. Herein we describe a total synthesis of the (±)-CC-1065 CPI subun