927652-16-2

Upstream product

• 951-77-9 2'-Deoxycytidine 
• 93-97-0 benzoic acid anhydride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 107-31-3 Methyl formate 
• 51549-38-3 N⁴-benzoyl-O^3',O^5'-bis(tert-butyldimethylsilyl)-2'-deoxycytidine 

Downstream Products

• 927652-17-3 N⁴-benzoyl-3',5'-bis-O-(tert-butyldimethylsilyl)-6-vinyl-2'-deoxycitidine 

Relevant academic research and scientific papers

Exploring the synthesis of masked phosphoramido 6-vinylcytidine derivatives as building blocks for cross-linking oligonucleotides

In the present work the synthesis of building blocks (2a,b), bearing a masked form of the reactive vinyl group bound to the C-6 position of a cytidine derivative, has been studied. The understanding of byproduct formation together with conformational considerations let us to plan a straightforward approach for the synthesis of the target compounds.