92884-93-0

Upstream product

• 10295-34-8 3-(4-Nitrophenyl)-1-phenyl-2,2-dichloroaziridine 
• 64-19-7 acetic acid 
• 67-66-3 chloroform 
• 149742-50-7 4-bromo-N-(4-nitrobenzylidene)aniline 
• 106-40-1 4-bromo-aniline 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 92884-99-6 N-(4-Bromo-phenyl)-2-chloro-2-(4-nitro-phenyl)-acetamide 
• 92885-00-2 N-(4-Bromo-phenyl)-2-hydroxy-2-(4-nitro-phenyl)-acetamide 
• 1393934-75-2 N-(4-bromophenyl)-N-[hydroxy(4-nitrophenyl)methyl]formamide 

Relevant academic research and scientific papers

Nanocrystalline magnesium oxide as a solid base catalyst promoted one pot synthesis of gem-dichloroaziridine derivatives under thermal conditions

In this study, efficient and mild synthesis of gem-dichloroaziridines from Schiff bases in the presence of nanocrystalline magnesium oxide/chloroform as a novel source of dichlorocarbene intermediate under thermal conditions have been described. The react

Sonocatalyzed facile and mild one pot synthesis of gem-dichloroaziridine derivatives under alkaline conditions

In this research, rapid and efficient preparation of 2,2-dichloro-1,3- diarylaziridines through the reaction of Schiff base compounds with dichlorocarbene yielded in situ from chloroform and sodium hydroxide without any phase transfer catalyst under ultrasonic irradiation is described. The advantages of this reaction are very short reaction times, excellent product yields, simplicity of the method and high purity of products.

A novel catalyst-free one-pot synthesis of some new N-(α- hydroxybenzyl)formamides by treatment of 2,2-dichloroaziridines with dimethyl sulfoxide and water under neutral conditions

A novel, mild, and efficient method is reported for the preparation of new N-(α-hydroxybenzyl)formamides in excellent yields and appropriate reaction times through the reaction of 2,2-dichloroaziridines with aqueous DMSO as the O-donor under neutral condi

Ultrasonic-assisted synthesis of 1,3-diaryl-2,2-dichloroaziridine derivatives in the presence of phase-transfer catalyst under low-concentration alkaline conditions

In this research, rapid and efficient preparation of 1,3-diaryl-2,2- dichloroaziridines through the reaction of Schiff base compounds with dichlorocarbene yielded in situ in the presence of cetyltrimethylammonium bromide (CTAB) as phase-transfer catalyst

Mild, convenient and efficient synthesis of novel 2,2-dichloro-1,3- diarylaziridines from Schiff bases by phase transfer CTAB catalysis under low concentration alkaline conditions

A mild and efficient method for preparation of novel 2,2-dichloro-1,3- diarylaziridines from Schiff base compounds in the presence of N-cetyl-N,N,N-trimethyl ammonium bromide (CTAB) as phase transfer catalyst has been described. The reaction is dramatical

1,3-DIARYL-2,2-DIHALOAZIRIDINES IN NITRATION AND BROMINATION REACTIONS

In the nitration of 3-(4-nitrophenyl)-1-phenyl-2,2-dichloroaziridine in acetic acid, 1-(o- and p-nitrophenyl)-derivatives are formed in a 35:65 ratio. 1,3-Diphenyl-2,2-dichloroaziridine undergoes opening of the three-membered ring under the same conditions, forming a mixture of o- and p-nitroanilides and 2-nitro-4-chloroanilides of 2-acetoxy (or 2-chloro)-2-phenylacetic acids.The bromination of 3-(4-nitrophenyl)-1-phenyl-2,2-dichloroaziridine in aqueous acetic acid leads to 1-(4-bromophenyl)-3-(4-nitrophenyl)-2,2-dichloroaziridine, while in a mixture of acetic acid and acetic anhydride it leads to the anilide of 2-bromo-2-phenylacetic acid and 2-bromo-N-(2,4-dibromophenyl)-1-(4-nitrophenyl)-2,2-dichloroethylamine.