929552-50-1Relevant academic research and scientific papers
The synthesis of a geminally perfluoro-tert-butylated β-amino acid and its protected forms as a potential pharmacokinetic modulator and reporter for peptide-based pharmaceuticals
Jiang, Zhong-Xing,Yu, Y. Bruce
, p. 1464 - 1467 (2007)
(Chemical Equation Presented) To modulate and report the pharmacokinetics of peptide-based pharmaceuticals, a novel geminally perfluoro-tert-butylated β-amino acid (βFa) and its Fmoc- and Boc-protected forms were designed and synthesized. βFa was incorpor
HIGHLY FLUORINATED β-AMINO ACIDS AND METHODS OF MAKING AND USING SAME
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Page/Page column 22-23; 32, (2008/06/13)
Disclosed are compounds having the structure: wherein Rla and Rlb are independently H, alkyl, F, or fluoroalkyl; wherein R2a, R2b, R2a', and R2b are independently H, alkyl, F, fluoroalkyl, aryl, or alkenyl; wherein R3 is OH, alkoxyl, NH2, alkylamino, or d
