930780-20-4Relevant academic research and scientific papers
Atropisomeric 3-(β-hydroxyethyl)-4-arylquinolin-2-ones as maxi-K potassium channel openers
Vrudhula, Vivekananda M.,Dasgupta, Bireshwar,Qian-Cutrone, Jingfang,Kozlowski, Edward S.,Boissard, Christopher G.,Dworetzky, Steven I.,Wu, Dedong,Gao, Qi,Kimura, Roy,Gribkoff, Valentin K.,Starrett Jr., John E.
, p. 1050 - 1057 (2008/02/02)
The synthesis of a series of 3-β-hydroxyethyl-4-arylquinolin-2-ones is described. These compounds contain hydrophilic and hydrophobic substituents ortho to the phenolic OH in the C ring of the quinolinone. Electrophysiological evaluation of the panel of c
