93087-50-4

Upstream product

• 92368-25-7 3-benzenesulfonyl-phenol 
• 17113-78-9 3-trimethylstannylanisole 
• 98-09-9 benzenesulfonyl chloride 
• 30723-54-7 1-methoxy-3-phenylsulfanyl-benzene 
• 66003-76-7 Diphenyliodonium triflate 
• 2398-37-0 3-methoxyphenyl bromide 
• 108-86-1 bromobenzene 
• 515-42-4 sodium phenylsulfonate 
• 217813-03-1 3-methoxy-2-(trimethylsilyl)phenyl-trifluoromethanesulfonate 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 1301268-25-6 5-methoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 873-55-2 sodium benzenesulfonate 
• 108-98-5 thiophenol 
• 100-66-3 methoxybenzene 

Downstream Products

• 7402-69-9 p-hydroxyphenyl p-tolyl sulfone 

Relevant academic research and scientific papers

Modulation of photochemical oxidation of thioethers to sulfoxides or sulfones using an aromatic ketone as the photocatalyst

We have developed an eco-friendly and chemo-selective photocatalytic synthesis of sulfoxides or sulfones via oxidation of sulfides (thioethers) at ambient temperature using air or O2 as the oxidant. An inexpensive thioxanthone was used as the photocatalyst. Our method offers excellent chemical yields and good functional group tolerance. The hydrogen bonding between hexafluoro-2-propanol (HFIP) and sulfoxides may play an important role in minimizing the over-oxidization of sulfoxides.

Synthesis method of diaryl sulfone compound (by machine translation)

The invention discloses a synthesis method of a diaryl sulfone compound, wherein the, reaction equation of the series of N - diarylsulfone compounds is prepared by (NFSI) sulfonylating the aromatic hydrocarbon under the non-metal condition with the source of the, benzenesulfonyl group as the benzenesulfonyl group, and: the reaction equation is as follows. STR3, #, STR2, #, STR2, #, #, #, # STR2. # STR2# STR2# STR2, , STR2 STR2 STR2 N - # (NFSI) STR2# STR2 STR2 STR2, #, # STR1 STR8# STR2 STR1 STR8. AlCl R3 , FeCl3 The other precious, and metals of, other metals such as the precious metals of, the other noble metals not cause the environment, to pollute, the environment and are suitable for the concise and high-efficiency synthesis of. the diarylsulfone compounds, and have good application prospects in the fields of organic synthesis, drug research and development and the like. (by machine translation)

A Class of Amide Ligands Enable Cu-Catalyzed Coupling of (Hetero)aryl Halides with Sulfinic Acid Salts under Mild Conditions

The amide derived from 4-hydroxy-l-proline and 2,6-dimethylaniline is a powerful ligand for Cu-catalyzed coupling of (hetero)aryl halides with sulfinic acid salts, allowing the formation of a wide range of (hetero)aryl sulfones from the corresponding (hetero)aryl halides at considerably low catalytic loadings. The coupling of (hetero)aryl iodides and sodium methanesulfinate proceeds at room temperature with only 0.5 mol % CuI and ligand, representing the first example for Cu-catalyzed arylation at both low catalytic loading and room temperature.

Nickel-Catalyzed Synthesis of Diaryl Sulfones from Aryl Halides and Sodium Sulfinates

A novel nickel-catalyzed cross-coupling of sulfinic acid salts with aryl halides is described. The reaction provides access to various diaryl sulfones in moderate to excellent yields. A broad range of functional groups and heteroaromatic compounds is tolerated under the reaction conditions.

Post-synthetically modified SBA-15 with NH2-coordinately immobilized iron-oxine: SBA-15/NH2-FeQ3 as a Fenton-like hybrid catalyst for the selective oxidation of organic sulfides

A new modified SBA-15 meso-material with NH2-coordinately immobilized "iron-oxine" was fabricated by stepwise covalent grafting of -NH2 and then NH2-coordinate immobilization of tris(8-quinolinolato)iron onto the channels of SBA-15. The structural properties and chemical nature of SBA-15/NH2-FeQ3 were characterized by FTIR, scanning electron microscopy (SEM), SEM-EDX/mapping, transmission electron microscopy (TEM), low angle X-ray diffraction (L-XRD), thermal gravimetric analysis (TGA), N2-adsorption-desorption isotherms (BET) and atomic absorption spectroscopy (AAS). A Fenton-like green and eco-friendly procedure for the catalytic oxidation of aromatic organic sulfides to sulfones using H2O2 was investigated for the synthesised Fe/SBA-15 catalyst. This porous catalyst was found to be reusable for ten runs without appreciable change in the activity, or the composition of the catalyst.

Visible-Light-Driven Silver-Catalyzed One-Pot Approach: A Selective Synthesis of Diaryl Sulfoxides and Diaryl Sulfones

An efficient one-pot approach for the synthesis of diaryl sulfoxides and diaryl sulfones using aryl thiols and aryl diazonium salts was developed. The use of a visible-light-driven silver catalysis and the subsequent singlet-oxygen-induced oxidation enabled selective synthesis of sulfoxides and sulfones in the absence of a photocatalyst. The reactions were carried out under mild reaction conditions; the desired products were obtained under air atmosphere at room temperature.

One-pot synthesis of aryl sulfones from organometallic reagents and iodonium salts

A transition-metal-free arylation of lithium, magnesium, and zinc sulfinates with diaryliodonium salts is described. The sulfinic acid salts were prepared from the reaction of the corresponding organometallic reagents and sulfur dioxide. Combination of the three single steps (preparation of the organometallic compound, sulfinate formation, and arylation) leads to a one-pot sequence for the synthesis of aryl sulfones from simple starting materials. The chemoselectivity of unsymmetrical diaryliodonium salts has been investigated. Potential and limitations of this method will be discussed.

Metal-free, high yielding synthesis of unsymmetrical biaryl, bi(heteroaryl), aryl vinyl, aryl alkyl sulfones via coupling of aryne with sulfinic acid salts

Here, we report a metal-free, high yielding method for the synthesis of unsymmetrical biaryl sulfones via coupling of aryne with sulfinic acid salts. The optimized condition also works efficiently for bi(heteroaryl), aryl vinyl and aryl alkyl sulfones. The present method took comparatively shorter reaction times and has good functional group compatibility. This journal is

Transition-metal-free C-S bond formation: A facile access to aryl sulfones from sodium sulfinates via arynes

Sulfones have been attractive targets for synthetic organic chemists owing to their immense applications in medicinal, material, and synthetic chemistry. In this context, an efficient transition-metal-free process has been demonstrated, wherein a broad range of alkyl/aryl/heteroaryl sodium sulfinates react with varyingly substituted aryne precursors (o-silyl aryl triflates) under mild reaction conditions to afford structurally diverse sulfones in good to excellent yields.

Palladium-catalyzed three-component diaryl sulfone synthesis exploiting the sulfur dioxide surrogate DABSO

SO(2) efficient: A three-component palladium-catalyzed coupling of aryl lithium compounds; sulfur dioxide (provided by the easy-to-handle solid surrogate, DABSO); and aryl, heteroaryl, and alkenyl (pseudo)halides yields a diverse library of sulfones. An electron-poor XantPhos-type ligand suppresses aryl-aryl exchange and is key to obtaining high yields.