93124-90-4

Basic information

• Product Name: 4H-1-Benzopyran-4-one,2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6,7-trimethoxy-
• Synonyms: AgeconyflavoneC
• CAS NO: 93124-90-4
• Molecular Formula: C20H20 O8
• Molecular Weight: 388.374
• Mol File: 93124-90-4.mol

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one,2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6,7-trimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one,2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6,7-trimethoxy-(93124-90-4)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one,2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6,7-trimethoxy-(93124-90-4)

Safety Data

• Hazardous Substances Data: 93124-90-4(Hazardous Substances Data)

Upstream product

• 89354-95-0 4'-benzyloxy-5,6,7,3',5'-pentamethoxyflavone 
• 22248-14-2 6-hydroxy-2,3,4-trimethoxyacetophenone 
• 14588-60-4 4-(benzyloxy)-3,5-dimethoxybenzoic acid 
• 89354-97-2 2-hydroxy-4'-benzyloxy-3',4,5,5',6-pentamethoxydibenzoylmethane 
• 89354-96-1 2-(3',5'-dimethoxy-4'-benzyloxy)benzoyloxy-4,5,6-trimethoxyacetophenone 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 642-71-7 3,4,5-trimethoxyphenol 

Downstream Products

• 29043-07-0 3',4',5,5',6,7-Hexamethoxyflavone 
• 83133-17-9 4',5-dihydroxyoxy-3',5',6,7-tetramethoxyflavone 

Relevant articles and documents

Synthesis and anti-proliferative activities of 5,6,7-trimethoxyflavones and their derivatives

A series of 5,6,7-trimethoxyflavones 1a-1g and their derivatives 2a-2g, 3a-3d, 4 and 5, including the natural products 5,6,7-trimethoxy-4’-hydroxyflavone (1a), 5,6,7,3’,4’ -pentamethoxyflavone (sinensetin, 1 b), 5,6,7-trimethoxy-3’,4’-methyl enedioxy flavone (1c), 5,6,7,3’-tetramethoxy-4,5’-methylenedioxyflavone (1e), 5,6,7, 3’,4’,5’-hextamethoxyflavone (1 g), 5-hydroxy-3,4,2’,3’,4’-pentamethoxy chal-cone (2 b), 5,4’-dihydroxy-6,7-dimethoxy flavone (cirsimaritin, 3a) and 5-hydroxy-6,7,3’, 4’-tetramethoxyflavone (5-demethylsinensetin, 3 b), 3,5,6,7,3’,4’-hexamethoxyflavone (3-methoxysinensetin, 4) and 5’-hydroxy-3,6,7,3’,4’-pentamethoxyflavone (5) were synthesized. Their anti-proliferative activity in?vitro was evaluated against a panel of four human cancer cell lines (Aspc-1, HCT-116, HepG-2 and SUN-5) by the CTG assay. The results showed that most of the synthetic compounds exhibited moderate to high anti-proliferative activities. In particular, compound 3c possess IC50 (5.30 μM) values below 10 μM against Aspc-1 cells and are worthy of further investigation.

Synthetic Studies on the Flavone Derivatives. XII. Synthesis of 2',3',5'- and 3',4',5'-Trioxygenated Flavones

Two unusual flavones, 5,5'-dihydroxy-2',3',6,7-tetramethoxyflavone (1) from Gardenia cramerii and 4',5-dihydroxy-3',5',6,7-tetramethoxyflavone (6) from Artemisia mesatlantia, and their position isomers were synthesized to investigate the structural correlation in terms of spectral data.The structure of the flavone from G. cramerii is discussed.Keywords: 5,5'-dihydroxy-2',3',6,7-tetramethoxyflavone; 2',5-dihydroxy-3',5',6,7-tetramethoxyflavone; 5-hydroxy-2',3',5',6,7-pentamethoxyflavone; 3',5-dihydroxy-4',5',6,7-tetramethoxyflavone; 4',5-dihydroxy-3',5',6,7-tetramethoxyflavone; 5-hydroxy-3',4',5',6,7-pentamethoxyflavone.