932393-86-7Relevant academic research and scientific papers
A facile organocatalyzed Michael addition of pyrazolines to α,β-unsaturated carbonyl compounds
Xie, Chen,Lu, Zhijin,Zhou, Wei,Han, Jianlin,Pan, Yi
, p. 6650 - 6653 (2013/01/15)
A new highly efficient cascade reaction of pyrazolines with α,β-unsaturated carbonyl compounds catalyzed by DBU was reported. The process underwent the first deprotection/Michael addition reaction to give 4-substituted pyrazoline derivatives, which were further converted into 4,4-di-substituted pyrazolone derivatives through the second deprotection/Michael reaction. The mechanism for this reaction was also studied.
Synthesis and antimicrobial activity of novel spirocompounds with pyrazolone and pyrazolthione moiety
Chande, Madhukar S.,Barve, Pravin A.,Suryanarayan, Vijay
, p. 49 - 53 (2008/09/18)
(Chemical Equation Presented) The paper focuses on the utility of 2-pyrazoline-5-ones and 2-pyrazoline-5-thiones as active Michael donors for the synthesis of novel spirocyclohexanone derivatives. The sulphur containing compounds when screened for antimicrobial activity showed promising inhibition of S.Typhi, S Aures and E Coli bacteria.
