138853-66-4Relevant articles and documents
Synthesis of 1-acyl-1,2-dihydro-3H-pyrazol-3-ones via Lewis acid-mediated rearransement of 3-acyloxypyrazoles
Maruoka, Hiroshi,Yamagata, Kenji,Okabe, Fumi,Tomioka, Yukihiko
, p. 859 - 865 (2006)
The unusual formation of 1-acyl-1,2-dihydro-3H-pyrazol-3-ones starting from 3-acyloxypyrazoles by Fries-type rearrangement is described. Under normal conditions, acylation of 2,4-dihydro-3H-pyrazol-3-ones 1 and 2 with acid chlorides or anhydrides in the p
A facile organocatalyzed Michael addition of pyrazolines to α,β-unsaturated carbonyl compounds
Xie, Chen,Lu, Zhijin,Zhou, Wei,Han, Jianlin,Pan, Yi
supporting information, p. 6650 - 6653 (2013/01/15)
A new highly efficient cascade reaction of pyrazolines with α,β-unsaturated carbonyl compounds catalyzed by DBU was reported. The process underwent the first deprotection/Michael addition reaction to give 4-substituted pyrazoline derivatives, which were further converted into 4,4-di-substituted pyrazolone derivatives through the second deprotection/Michael reaction. The mechanism for this reaction was also studied.