933-87-9

Basic information

• Product Name: 1-methyl-5-bromo-4-nitroimidazole
• Synonyms: 1-methyl-5-bromo-4-nitroimidazole;5-broMo-1-Methyl-4-nitro-1H-iMidazole
• CAS NO: 933-87-9
• Molecular Formula: C₄H₄BrN₃O₂
• Molecular Weight: 206
• Mol File: 933-87-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 333.9°Cat760mmHg
• Flash Point: 155.7°C
• Appearance: /
• Density: 2.04g/cm³
• Vapor Pressure: 0.000257mmHg at 25°C
• Refractive Index: 1.688
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-methyl-5-bromo-4-nitroimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-5-bromo-4-nitroimidazole(933-87-9)
• EPA Substance Registry System: 1-methyl-5-bromo-4-nitroimidazole(933-87-9)

Safety Data

• Hazardous Substances Data: 933-87-9(Hazardous Substances Data)

Usage

Uses

5-Bromo-1-methyl-4-nitro-1H-imidazole, is a buliding blcok used in the synthesis of various compounds such as, 5,5''-Thiobis[1-methyl-4-nitro-1H-Imidazole (T350205).

InChI:InChI=1/C4H4BrN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3

Upstream product

• 6963-65-1 4-bromo-5-nitro-1H-imidazole 
• 77-78-1 dimethyl sulfate 
• 7664-93-9 sulfuric acid 
• 186581-53-3 diazomethane 
• 6963-65-1 5-bromo-4-nitro-1H-imidazole 

Downstream Products

• 17024-55-4 1-Methyl-4-nitro-5-piperidinoimidazole 
• 80812-44-8 1-methyl-4-nitro-5-(phenylthio)-1H-imidazole 
• 80348-54-5 1-methyl-4-nitro-5-(phenylsulfonyl)-1H-imidazole 
• 5702-78-3 1-methyl-4-nitro-5-[4-acetamido(phenylsulfonyl)]-1H-imidazole 
• 108375-63-9 1-methyl-4-nitro-5-(4-methylphenylsulfonyl)-1H-imidazole 
• 1070980-45-8 2-[(1-methyl-4-nitro-5-imidazolyl)thio]-5-(4-methoxyphenyl)-1,3,4-thiadiazole 
• 18383-80-7 1-methyl-5-(4'-methylphenyl)thio-4-nitroimidazole 
• 40648-96-2 1-methyl-4-nitro-1H-imidazole-5-carbonitrile 
• 35687-41-3 5-Methoxy-1-methyl-4-nitroimidazole 

Relevant articles and documents

Synthesis and in vitro antibacterial activity of new 2-(1-methyl-4-nitro- 1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles

In the present study we report the synthesis and antibacterial activity of a new series 2-(1-methyl-4-nitro-1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles (6a-c). Compounds 6a-c were tested in vitro by the conventional agar dilution method against a panel of microorganisms including gram-negative and gram-positive bacteria. Compound 6b with 5-(5-nitrofuran-2-yl)-residue on 1,3,4-thiadiazole scaffold have shown promising antibacterial activities against gram-positive bacteria including Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis.

A New and Unequivocal Method for Establishing the Position of N-Glycosylation of Unsymmetrically C-Substituted Imidazoles

N-Substitution of an unsymmetrically C-substituted imidazole can give rise to a pair of structurally isomeric derivatives and to differentiate between such related compounds can be difficult.Two methods, one spectroscopic and one chemical, for ascertaining the orientation of such N-substitutions are described, with particular application to the establishment of the direction of N-ribosidation of a series of halogeno nitroimidazoles.