933800-38-5Relevant academic research and scientific papers
TRIAZOLE AGONISTS OF THE APJ RECEPTOR
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Paragraph 0294; 0295, (2016/12/07)
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.
Three-component reaction involving metal-free heteroannulation of N-Boc-3-amido indole, aryl aldehydes, and aromatic alkynes under microwave conditions: Synthesis of highly diversified δ-carbolines
Sharma, Sudhir K.,Mandadapu, Anil K.,Saifuddin, Mohammad,Gupta, Sahaj,Agarwal, Piyush K.,Mandwal, Ashok K.,Gauniyal, Harsh M.,Kundu, Bijoy
experimental part, p. 6022 - 6024 (2010/11/18)
An efficient synthesis toward highly diversified δ-carbolines via one-pot multicomponent reaction using N-Boc-3-amido indoles, aryl aldehydes, and aromatic terminal alkynes under microwave conditions has been described.
Efficient reductive acylation of 3-nitroindoles
Roy, Sujata,Roy, Sudipta,Gribble, Gordon W.
, p. 1531 - 1533 (2008/09/19)
3-Nitroindoles are catalytically reduced by hydrogen on palladium/carbon to furnish the relatively unstable aminoindoles, which in the presence of carboxylic acid anhydrides afford good to excellent yields of the corresponding N-acylaminoindoles. 2-Nitroi
Convenient synthesis of masked aminoindoles by indium mediated one-pot reductive acylation of 3- and 2-nitroindoles
Roy, Sujata,Gribble, Gordon W.
, p. 51 - 56 (2007/10/03)
Unstable 3- and 2-aminoindoles arc generated in situ by indium mediated reduction of 3- and 2-nitroindoles and capped as the stable amides (or carbamate) in moderate to high yields under mild conditions in a one-pot procedure.
