934662-91-6

Basic information

• Product Name: XL-518 raceMate
• Synonyms: GDC-0973 (raceMate);XL-518 raceMate;CobiMetinib (raceMate);1-[[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]carbonyl]-3-(piperidin-2-yl)azetidin-3-ol;Cobimetinib (GDC-0973) racemate
• CAS NO: 934662-91-6
• Molecular Formula: C21H21F3IN3O2
• Molecular Weight: 531.3100196
• Mol File: 934662-91-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: XL-518 raceMate(CAS DataBase Reference)
• NIST Chemistry Reference: XL-518 raceMate(934662-91-6)
• EPA Substance Registry System: XL-518 raceMate(934662-91-6)

Safety Data

• Hazardous Substances Data: 934662-91-6(Hazardous Substances Data)

Usage

General Description

XL-518 raceMate is a chemical additive designed to improve the performance of racing fuels. It is formulated to increase the octane rating of the fuel, providing a higher resistance to engine knocking and pre-ignition, which can lead to improved power output and efficiency. Additionally, XL-518 raceMate contains detergents that help clean and maintain fuel system components, leading to reduced engine deposits and improved overall engine performance. This chemical additive is specifically designed for use in high-performance racing engines and is intended to be added to unleaded gasoline at recommended ratios to maximize its benefits.

Upstream product

• 153749-89-4 2-cyanopiperidine-1-carboxylic acid tert-butyl ester 
• 934664-27-4 1,1-dimethylethyl 2-(3-hydroxy-1-{[(phenylmethyl)oxy]carbonyl}azetidin-3-yl)piperidine-1-carboxylate 
• 934666-39-4 (R,S) tert-butyl 2-(3-hydroxy-3-azetidinyl)-1-piperidinecarboxylate 
• 98303-20-9 1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid 
• 4043-87-2 pipecolic Acid 
• 388077-74-5 rac-N-(tert-butoxycarbonyl)piperidine-2-carboxamide 

Relevant articles and documents

PROCESS FOR THE PRODUCTION OF COBIMETINIB

The present invention relates to a novel route of synthesis for the production of enantiomerically pure Cobimetinib, new intermediates in the synthesis of Cobimetinib and an amorphous Cobimetinib hemifumarate salt comprising a high salt content.