93472-62-9

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 75268-14-3 4-hydroxy-N-(2-hydroxyethyl)-benzamide 

Downstream Products

• 87495-31-6 disoxaril 
• 98033-84-2 5-{6-[4-(4,5-Dihydro-2-oxazolyl)phenoxy]hexyl}-3-methylisoxazole 
• 98033-95-5 5-{4-[4-(4,5-dihydro-2-oxazolyl)phenoxy]butyl}-3-methylisoxazole 
• 98034-30-1 5-(5-(4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methylisoxazole 
• 98033-91-1 5-{8-[4-(4,5-Dihydro-2-oxazolyl)phenoxy]octyl}-3-methylisoxazole 

Relevant academic research and scientific papers

Synthesis and Structure-Activity Studies of Some Disubstituted Phenylisoxazoles against Human Picornavirus

A number 2,6-disubstituted analogues of disoxaril, a broad spectrum antipicornavirus agent, have been prepared and evaluated against several rhinovirus serotypes.A QSAR study revealed that the mean MIC () against five rhinovirus serotypes correlated well with log P.The 2,6-dichloro analogue, 15, was highly effective in vitro against rhinoviruses with an MIC80 of 0.3 μM, as well as against several enteroviruses, and was also effective in preventing paralysis in mice infected with coxsackievirus A-9.

[[(4,5-Dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles. Inhibitors of picornavirus uncoating

A series of [[(4,5-dihydro-2-oxazolyl)phenoxy]alkyl]isoxazoles has been synthesized and evaluated as antipicornavirus agents. The effect of alkyl groups in the 4- and 5-position of the oxazoline ring, as well as the alkyl chain length, on antiviral activi