934842-69-0

Basic information

• Product Name: 4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol
• Synonyms: 4-(2-(Benzyl(6-(4-phenylbutoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol;4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol; 1,3-BENZENEDIMETHANOL, 4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL](PHENYLMETHYL)AMINO]METHYL]-
• CAS NO: 934842-69-0
• Molecular Formula: C₃₂H₄₃NO₄
• Molecular Weight: 505.695
• Mol File: 934842-69-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 662.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.125
• PKA: 9.96±0.31(Predicted)
• CAS DataBase Reference: 4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol(934842-69-0)
• EPA Substance Registry System: 4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol(934842-69-0)

Safety Data

• Hazardous Substances Data: 934842-69-0(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl](phenylmethyl)amino]methyl]-1,3-benzenedimethanol is a complex chemical compound with a long and detailed molecular structure. It contains hydroxy, benzene, phenyl, and amine functional groups, as well as several carbon chains of varying lengths. The compound is a type of benzenedimethanol and is likely to have pharmaceutical or biological applications, given its complex structure and functional groups. However, further research and analysis would be needed to fully understand the potential uses and properties of this chemical.

Upstream product

• 97664-55-6 N-[6-(4-phenylbutoxy)hexyl]benzenemethanamine 
• 94749-73-2 6-bromohexyl 4-phenylbutyl ether 
• 115787-50-3 5-(2-bromoacetyl)-2-hydroxybenzaldehyde 
• 90-02-8 salicylaldehyde 
• 3360-41-6 4-phenyl-butan-1-ol 
• 629-03-8 1 ,6-dibromohexane 
• 163923-19-1 2-hydroxy-5-<<<6,6-(4-phenylbutoxy)hexylbenzyl>amino>acetyl>benzaldehyde 

Downstream Products

• 135271-49-7 salmeterol xinafoate 
• 89365-50-4 salmeterol 

Relevant articles and documents

Preparation method of salmeterol base

The invention discloses a preparation method of salmeterol. The method includes the following steps: carrying out a condensation reaction on a compound 2 and a compound 3 under an alkaline condition to obtain an intermediate 4; carrying out acidic hydrolysis to obtain an intermediate 5, and reducing the intermediate 5 to obtain an intermediate 6; and removing a benzyl group from the intermediate 6 by using palladium on carbon (Pd/C) to obtain a salmeterol base. The preparation method has the advantages of mild reaction conditions, simple post-treatment, low cost, high yield high product purity, and easiness in realization of industrialization.

PROCESS FOR THE PREPARATION OF SALMETEROL XINAFOATE

The present invention relates to an improved process for the preparation of Salmeterol Xinafoate of Formula (I).

A new synthetic approach to salmeterol

In the present work a short and convenient route for the synthesis of salmeterol from salicylaldehyde has been developed.