93523-64-9Relevant academic research and scientific papers
Reaction of 2,2-Difluorovinyl Ketones with Heteroatom Nucleophiles: A General One-Pot Synthesis of α-Oxoketene Acetals
Ichikawa, Junji,Kobayashi, Masakuni,Yokota, Naoyuki,Noda, Yasuharu,Minami, Toru
, p. 11637 - 11646 (1994)
2,2-Difluorovinyl ketones readily react with heteroatom nucleophiles such as thiols, alcohols, and amines to undergo stepwise replacement of the two fluorine atoms via addition-elimination process.The reaction affords α-oxoketene acetals including S,S-, N
