Reaction of 2,2-Difluorovinyl Ketones with Heteroatom Nucleophiles: A General One-Pot Synthesis of α-Oxoketene Acetals

DOI: 10.1016/S0040-4020(01)85658-1

Source and publish data:

Tetrahedron p. 11637 - 11646 (1994)

Update date:2022-08-06

Topics:

Authors:

Ichikawa, Junji

Kobayashi, Masakuni

Yokota, Naoyuki

Noda, Yasuharu

Minami, Toru

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)85658-1

2,2-Difluorovinyl ketones readily react with heteroatom nucleophiles such as thiols, alcohols, and amines to undergo stepwise replacement of the two fluorine atoms via addition-elimination process.The reaction affords α-oxoketene acetals including S,S-, N

Full text of DOI:10.1016/S0040-4020(01)85658-1

Products guided by the article

Product name:Lithium, [2,2-difluoro-1-[[(4-methylphenyl)sulfonyl]oxy]ethenyl]-

Cas No:93523-64-9

R&D Labs maybe for 93523-64-9

GM CHMICAL CO., LTD

Contact:0086-21-80264647

Address:RM 202, NO 1602 West Zhongshan Rd, Shanghai, China
C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Anhui Biochem United Pharmaceutical Co., Ltd.

Contact:0086 551 5167062 / 5228268

Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
Wuhan Sunrise Pharmaceutical Technology Co., Ltd

Contact:+86-27-83314682

Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China

Relevant to this article

Knoevenagel condensation of the diphosphine ligand 4,5- bis(diphenylphosphino)-4-cyclopentene-1,3-dione with 9-anthracenecarboxaldehyde: Synthesis of the second-generation ligand 2-(anthracen-9-ylidene)-4,5- bis(diphenylphosphino)-4-cyclopentene-1,3-dione

Doi:10.1007/s10870-006-9125-1
(2006)
Synthesis of urine drug metabolites: glucuronic acid glycosides of phenol intermediates

Doi:10.1016/j.carres.2007.01.014
(2007)
Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium thalassospira sp.

Doi:10.1021/ol070294u
(2007)
Regioselective Synthesis of 2-Vinylanilines Using O-aroyloxycarba-mates by Sequential Decarboxylation/Amination/Heck Reaction

Doi:10.1021/acs.joc.7b01020
(2017)
BROMINE OXIDATION OF 1,2-O-ISOPROPYLIDINE-α-D-GLUCOFURANOSE AND SUCROSE

Doi:10.1016/0008-6215(80)90006-3
(1980)
Electron-accepting conjugated materials based on 2-Vinyl-4,5- dicyanoimidazoles for application in organic electronics

Doi:10.1021/jo802720m
(2009)

Article Doi