93598-41-5Relevant academic research and scientific papers
Enantioselective synthesis and antimicrobial activities of tetrahydro-β-carboline diketopiperazines
Ma, Yangmin,Wu, Hao,Zhang, Jin,Li, Yanchao
, p. 656 - 662 (2013/09/24)
A series of single isomers tetrahydro-β-carboline diketopiperazines were stereoselectively synthesized starting from l-tryptophan methyl ester hydrochloride and six aldehydes through a four-step reaction including Pictet-Spengler reaction, crystallization-induced asymmetric transformations (CIAT), Schotten-Baumann reaction, and intramolecular ester amidation. The chemical structures were characterized by nuclear magnetic resonance (NMR) and elemental analysis, among which two compounds were determined by x-ray single crystal diffraction. Moreover, antimicrobial activities of all the compounds were also tested. Chirality 25:656-662, 2013. 2013 Wiley Periodicals, Inc.
Methyl 1-imidazolecarbodithioate as a thiocarbonyl transfer reagent: a facile one-pot, three-component synthesis of novel 2-substituted-5-aryl-1-oxo-3-thioxo-1,2,3,5,11,11a-hexahydro-6H-imidazo- [1,5-b]-β-carbolines
Singh, Balendu,Sundaram,Misra, Nimesh C.,Ila, Hiriyakkanavar
experimental part, p. 366 - 369 (2009/04/19)
An efficient one-pot, three-component synthesis of novel 2-substituted-5-aryl-1-oxo-3-thioxo-1,2,3,5,11,11a-hexahydro-6H-imidazo- [1,5-b]-β-carbolines employing 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylates, primary amines (or amino acid esters) an
