936328-58-4

Basic information

• Product Name: Benzenemethanol, 3,4-difluoro-2-hydroxy-
• Synonyms: Benzenemethanol, 3,4-difluoro-2-hydroxy-;3,4-difluoro-2-hydroxyBenzenemethanol
• CAS NO: 936328-58-4
• Molecular Formula: C₇H₆F₂O₂
• Molecular Weight: 160.12
• Mol File: 936328-58-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenemethanol, 3,4-difluoro-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3,4-difluoro-2-hydroxy-(936328-58-4)
• EPA Substance Registry System: Benzenemethanol, 3,4-difluoro-2-hydroxy-(936328-58-4)

Safety Data

• Hazardous Substances Data: 936328-58-4(Hazardous Substances Data)

Usage

Physical properties

Colorless liquid with a faint odor, soluble in water and ethanol

Common uses

Intermediate in pharmaceutical and agrochemical synthesis, building block in flavoring agents and fragrance ingredients

Properties

Antioxidant and antimicrobial

Medical applications

Potential for inhibiting growth of certain cancer cells

Versatility

Wide range of uses in various industries

Upstream product

• 50-00-0 formaldehyd 
• 6418-38-8 2,3-difluorophenol 
• 67-56-1 methanol 
• 189283-51-0 3,4-difluoro-2-hydroxybenzoic acid 

Downstream Products

• 936328-59-5 (3,4-difluoro-2-hydroxybenzyl)(triphenyl)phosphonium bromide 
• 502762-95-0 3,4-difluoro-2-hydroxy-benzaldehyde 
• 1035155-97-5 ethyl (2E)-3-(3,4-difluoro-2-hydroxyphenyl)-2-propenoate 
• 1035155-99-7 ethyl 3-(3,4-difluoro-2-hydroxyphenyl)-2-propanoate 

Relevant articles and documents

Water-promoted ortho-selective monohydroxymethylation of phenols in the NaBO2 system

Water-promoted ortho-selective monohydroxymethylation of phenols in the NaBO2 system generates salicyl alcohols in 65-97% yields. A remarkable rate-enhancement by water was observed, and NaBO2 appeared to serve the dual role of a suitable base and an efficient chelating reagent. This protocol possesses many advantages such as short reaction times, expanded substrate scope, and high mono- and regio-selectivities. The experimental results were explained by the calculations based on local ionisation energy minima, leading to a possible reaction mechanism.

NOVEL 1 -BENZYL-4-PIPERIDINAMINES THAT ARE USEFUL IN THE TREATMENT OF COPD AND ASTHMA

The invention provides 1 -benzyl- 4 -piperidinamines of the general formula (I), processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are useful in the treatment of respiratory diseses such a