936641-30-4

Basic information

• Product Name: (Z)-2-(2-tert-butoxycarbonylamino-phenyl)-3-phenyl-acrylic acid
• Synonyms: (Z)-2-(2-tert-butoxycarbonylamino-phenyl)-3-phenyl-acrylic acid
• CAS NO: 936641-30-4
• Molecular Weight: 339.391
• Mol File: 936641-30-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-(2-tert-butoxycarbonylamino-phenyl)-3-phenyl-acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2-tert-butoxycarbonylamino-phenyl)-3-phenyl-acrylic acid(936641-30-4)
• EPA Substance Registry System: (Z)-2-(2-tert-butoxycarbonylamino-phenyl)-3-phenyl-acrylic acid(936641-30-4)

Safety Data

• Hazardous Substances Data: 936641-30-4(Hazardous Substances Data)

Upstream product

• 78839-75-5 2-bromo-N-(tert-butoxycarbonyl)aniline 
• 936641-28-0 cis-(2-styryl-phenyl)carbamic acid tert-butyl ester 
• 124-38-9 carbon dioxide 

Downstream Products

• 3359-49-7 3-benzylideneoxindole 

Relevant articles and documents

Development and application of a direct vinyl lithiation of cis-stilbene and a directed vinyl lithiation of an unsymmetrical cis-stilbene

Equation Presented The vinyl deprotonation of cis-stilbene can be readily achieved using s-BuLi in THF at -25°C. The generated 1-lithio-1,2- diphenylethene undergoes an in situ Z-to-E isomerization, and subsequent reaction with electrophiles results in an efficient stereoselective synthesis of trisubstituted alkenes. A directed vinyl lithiation of the unsymmetrical cis-stilbene 2-styryl-phenyl-carbamic acid tert-butyl ester can be achieved regioselectively, thereby expanding this methodology for further synthetic applications in indole chemistry.