937-22-4

Usage

Uses

Used in Organic Synthesis:
p-Chloroperbenzoic acid is used as a selective oxidant for converting alcohols, alkenes, and sulfides into their corresponding carbonyl compounds, epoxides, and sulfoxides, respectively. Its high reactivity and selectivity make it a valuable tool for chemists working on complex organic transformations.
Used in Laboratory Research:
In the laboratory setting, p-Chloroperbenzoic acid is employed as an alternative to other oxidizing agents such as potassium permanganate or chromic acid. Its strong oxidizing properties and ability to perform specific conversions make it a preferred choice for various chemical reactions and analyses.
Used in Chemical Education:
Due to its unique properties and applications, p-Chloroperbenzoic acid is also utilized in educational settings to teach students about oxidation reactions and the importance of safety in chemical experiments.
Used in Industrial Applications:
Although the primary use of p-Chloroperbenzoic acid is in laboratory research, its potential applications in industrial settings for specific chemical conversions and processes are also being explored, with the necessary safety precautions in place.

Upstream product

• 94-17-7 bis(4-chlorobenzoyl)peroxide 
• 124-41-4 sodium methylate 
• 74-11-3 para-chlorobenzoic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 106-43-4 para-chlorotoluene 
• 122-01-0 4-chloro-benzoyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 56391-39-0 C₂₀H₁₃Cl₂IO₆ 
• 35295-65-9 p-Chlorobenzoyl-p-toluolsulfonylperoxid 
• 68257-64-7 Diphenylmethylencarbamoyl-p-chlor-benzoperoxid 
• 179316-62-2 4-(4-chlorobenzylsulfinyl)-1-hydroxypyrrolo[1,2-d][1.2.4]triazine 
• 1241915-81-0 2-(difluoro(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)-7-(methylsulfonyl-methyl)quinazolin-4-amine 

Relevant academic research and scientific papers

Aerobic oxidation of aldehydes to acids with N-hydroxyphthalimide derivatives

The N-hydroxyphthalimide derivative-mediated aerobic oxidation of a selection of aldehydes to the corresponding carboxylic acids in air is described. This reaction proceeds via rearrangement of the Creigee (carboxylic peracid) intermediate and/or by the treatment of H2O and/or sulfides. Optimization of reaction conditions established NHNPI (14) as a mild catalyst for the oxidation reaction in MeCN under an atmosphere of air.

One-pot epoxidation of alkenes using aerobic photoperoxidation of toluenes

We developed an aerobic photooxidative synthesis of peroxybenzoic acids from toluenes using anthraquinone-2-carboxylic acid (AQN-2-CO2H) as a photocatalyst. We also found a one-pot epoxidation reaction of alkenes using 4-tert-butylperoxybenzoic acid produced in situ by aerobic photooxidative synthesis.

PHASE TRANSFER CATALYSED PEROXIDATION OF CARBOXYLIC ACIDS WITH POTASSIUM PERSULFATE

Aqueous solution of potassium persulfate converts water-insoluble carboxylic acids in ether (or dichloromethane), to peracids in a yield of 80-90percent under the catalytic influence of benzyltriethylammonium chloride (BTEAC) or polyethyleneglycol (PEG-400).The reaction is further catalyzed kinetically in presence of a sulfonated polymer.

PREPARATION OF CHLOROPERBENZOIC ACIDS.

A method was recently proposed whereby an acyl chloride is reacted with 30% hydrogen peroxide at room temperature in aqueous alcoholic solution in presence of potassium hydroxide and a stabilizer (magnesium sulfate). The resultant solution of the salt of the peroxy acid is acidified with sulfuric acid, and the liberated acid is extracted with chloroform. The objective of this research is to examine the possibility of using this method for preparation of chloroperbenzoic acids and to study the influence of the principal synthesis parameters on the yield and quality of the products. Based on experimental results, it is found that the process can be intensified considerably by decrease of the relative amount of solvent used.