937596-55-9 Usage
Fluoroaniline derivative
A compound derived from aniline by replacing one hydrogen atom with a fluorine atom, resulting in a 5-fluoroaniline group.
Benzene ring
A six-carbon ring structure with alternating single and double bonds, which is a key structural component of many organic compounds.
Aniline group
A functional group consisting of a nitrogen atom bonded to a hydrogen atom and a phenyl ring (-NH2), which imparts basic properties to the compound.
Diverse reactivity
The compound can undergo various chemical reactions due to the presence of different functional groups, making it a versatile building block in synthesis.
Potential biological activity
The compound may exhibit biological effects or interact with biological systems, making it a candidate for pharmaceutical and agrochemical development.
Building block in pharmaceuticals and agrochemicals synthesis
Due to its reactivity and potential biological activity, 2-(benzyloxy)-5-fluoroaniline is commonly used as a starting material or intermediate in the production of drugs and agrochemicals.
Benzyloxy group
A functional group consisting of a benzene ring attached to an oxygen atom (-OCH2Ph), which provides additional reactivity and attachment points for combinatorial chemistry.
Combinatorial chemistry and drug discovery
The benzyloxy group makes the compound suitable for attachment to solid supports, allowing for the rapid synthesis and screening of large libraries of related compounds in drug discovery and combinatorial chemistry.
Health and environmental hazards
Proper handling and management of 2-(benzyloxy)-5-fluoroaniline are essential to avoid potential risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 937596-55-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,7,5,9 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 937596-55:
(8*9)+(7*3)+(6*7)+(5*5)+(4*9)+(3*6)+(2*5)+(1*5)=229
229 % 10 = 9
So 937596-55-9 is a valid CAS Registry Number.
937596-55-9Relevant articles and documents
7-HYDROXY-SPIROPIPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR
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Paragraph 00150, (2014/02/16)
The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of Ρ2Y1 receptor and may be used as medicaments in the treatment and/or prophylaxis of thromboembolic disorders.
An examination of the palladium/Mor-DalPhos catalyst system in the context of selective ammonia monoarylation at room temperature
Alsabeh, Pamela G.,Lundgren, Rylan J.,McDonald, Robert,Johansson Seechurn, Carin C. C.,Colacot, Thomas J.,Stradiotto, Mark
supporting information, p. 2131 - 2141 (2013/03/14)
An examination of the [{Pd(cinnamyl)Cl}2]/Mor-DalPhos (Mor-DalPhos=di(1-adamantyl)-2-morpholinophenylphosphine) catalyst system in Buchwald-Hartwig aminations employing ammonia was conducted to better understand the catalyst formation process and to guide the development of precatalysts for otherwise challenging room-temperature ammonia monoarylations. The combination of [{Pd(cinnamyl)Cl}2] and Mor-DalPhos afforded [(κ 2-P,N-Mor-DalPhos)Pd(η1-cinnamyl)Cl] (2), which, in the presence of a base and chlorobenzene, generated [(κ2-P,N- Mor-DalPhos)Pd(Ph)Cl] (1 a). Halide abstraction from 1 a afforded [(κ3-P,N,O-Mor-DalPhos)Pd(Ph)]OTf (5), bringing to light a potential stabilizing interaction that is offered by Mor-DalPhos. An examination of [(κ2-P,N-Mor-DalPhos)Pd(aryl)Cl] (1 b-f) and related precatalysts for the coupling of ammonia and chlorobenzene at room temperature established the suitability of 1 a in such challenging applications. The scope of reactivity for the use of 1 a (5 mol %) encompassed a range of (hetero)aryl (pseudo)halides (X=Cl, Br, I, OTs) with diverse substituents (alkyl, aryl, ether, thioether, ketone, amine, fluoro, trifluoromethyl, and nitrile), including chemoselective arylations. Copyright
