93856-98-5

Basic information

• Product Name: 4-CHLORO-2-PROPYL-PYRIDINE
• Synonyms: 4-CHLORO-2-PROPYL-PYRIDINE;Pyridine, 4-chloro-2-propyl-
• CAS NO: 93856-98-5
• Molecular Formula: C₈H₁₀ClN
• Molecular Weight: 155.6247
• EINECS: 299-133-7
• Mol File: 93856-98-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 196.3°Cat760mmHg
• Flash Point: 90.3°C
• Appearance: /
• Density: 1.081g/cm³
• Vapor Pressure: 0.565mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CHLORO-2-PROPYL-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-PROPYL-PYRIDINE(93856-98-5)
• EPA Substance Registry System: 4-CHLORO-2-PROPYL-PYRIDINE(93856-98-5)

Safety Data

• Hazardous Substances Data: 93856-98-5(Hazardous Substances Data)

Usage

General Description

4-CHLORO-2-PROPYL-PYRIDINE is a chemical compound with the molecular formula C8H10ClN. It is a pyridine derivative with a chlorine atom and a propyl group attached to the second carbon atom of the pyridine ring. 4-CHLORO-2-PROPYL-PYRIDINE is used in the synthesis of various pharmaceuticals and agrochemicals, and it is also used as an intermediate in organic reactions. 4-CHLORO-2-PROPYL-PYRIDINE is a colorless to light yellow liquid with a pungent odor, and it is important to handle it with caution due to its potential health hazards.

InChI:InChI=1/C8H10ClN/c1-2-3-8-6-7(9)4-5-10-8/h4-6H,2-3H2,1H3

Upstream product

• 626-61-9 4-Chloropyridine 
• 3678-63-5 4-chIoro-2-methylpyridine 
• 75-03-6 ethyl iodide 
• 132410-17-4 4-chloro-1-(phenoxycarbonyl)-2-n-propyl-1,2-dihydropyridine 

Downstream Products

• 139179-03-6 ethyl 8-chloro-1-ethyl-4H-quinolizin-4-one-3-carboxylate 
• 875126-10-6 2-[2-(4-chloro-pyridin-2-yl)-1-(4-methoxy-benzylsulfanyl)-butylidene]-malonic acid diethyl ester 
• 875126-12-8 ethyl 8-chloro-1-ethyl-2-(4-methoxybenzylsulfanyl)-4-oxo-4H-quinolizine-3-carboxylate 

Relevant articles and documents

8-N-substituted-2H-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents

The invention provides compounds and salts of Formula I and Formula II: which possess antimicrobial activity. The invention also provides novel synthetic intermediates useful in making compounds of Formula I and Formula II. The variables A1, A8, R2, R3, R5, R6, R7, and R9 are defined herein. Certain compounds of Formula I and Formula II disclosed herein are potent and selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula I or Formula II and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula I or Formula II as the only active agent or may contain a combination of compounds of Formula I and/or Formula II and one or more other active agents. The invention also provides methods for treating microbial and protozoal infections in animals.

1-THIA-2,4A-DIAZA-CYCLOPENTA[B]NAPHTHALENE-3,4-DIONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS

The invention provides compounds and salts of Formula (I) and Formula (II) which possess antimicrobial activity. The invention also provides novel synthetic intermediates useful in making compounds of Formula (I) and Formula (II). The variables A1, A8, R2, R3, R5, R6, R7, and R9 are defined herein. Certain compounds of Formula (I) and Formula (II) disclosed herein are potent and selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula (I) or Formula (II) and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula (I) or Formula (II) as the only active agent or may contain a combination of a compound of Formula (I) or Formula (II) and one or more other active agents. The invention also provides methods for treating microbial infections in animals.

Quinolizinone type compounds

Antibacterial compounds having the formula STR1 and the pharmaceutically acceptable salts, esters and amides thereof, preferred examples of which include those compounds wherein A is =CR6 --; R1 is cycloalkyl of from three to eight carbon atoms or substituted phenyl; R2 is selected from the group consisting of STR2 R3 is halogen; R4 is hydrogen, loweralkyl, a pharmaceutically acceptable cation, or a prodrug ester group; R5 is hydrogen, loweralkyl, halo(loweralkyl), or --NR13 R14 ; and R6 is halogen, loweralkyl, halo(loweralkyl), hydroxy-substituted loweralkyl, loweralkoxy(loweralkyl), loweralkoxy, or amino(loweralkyl), as well as pharmaceutical compositions containing such compounds and the use of the same in the treatment of bacterial infections.