4-Chloro-2-propylpyridine

Base Information

• Chemical Name: 4-Chloro-2-propylpyridine
• CAS No.: 93856-98-5
• Molecular Formula: C8H10 Cl N
• Molecular Weight: 155.627
• Hs Code.: 2933399090
• European Community (EC) Number: 299-133-7
• DSSTox Substance ID: DTXSID80239790
• Nikkaji Number: J320.582G
• Wikidata: Q83122260
• Mol file: 93856-98-5.mol

Synonyms:4-Chloro-2-propylpyridine;4-Chloro-2-propyl-pyridine;93856-98-5;EINECS 299-133-7;SCHEMBL1507007;DTXSID80239790;XACBIHLRDPQCGQ-UHFFFAOYSA-N;AKOS006342357;SB40096;AC-20597

Chemical Property of 4-Chloro-2-propylpyridine

Chemical Property:

• Vapor Pressure: 0.565mmHg at 25°C
• Boiling Point: 196.3°Cat760mmHg
• Flash Point: 90.3°C
• PSA: 12.89000
• Density: 1.081g/cm³
• LogP: 2.68750
• Storage Temp.: 2-8°C
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 155.0501770
• Heavy Atom Count: 10
• Complexity: 95.3

Purity/Quality:

97% ^*data from raw suppliers

4-CHLORO-2-PROPYL-PYRIDINE 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1=NC=CC(=C1)Cl

Technology Process of 4-Chloro-2-propylpyridine

There total 5 articles about 4-Chloro-2-propylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-chIoro-2-methylpyridine (3678-63-5) + ethyl iodide (75-03-6) → 4-chloro-2-propylpyridine (93856-98-5)

Guidance literature:

4-chIoro-2-methylpyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

ethyl iodide; In tetrahydrofuran; at -78 - -30 ℃; for 1.5h;

DOI:10.1021/jm051066d

Reference yield:

ethyl iodide (75-03-6) → 4-chloro-2-propylpyridine (93856-98-5)

Guidance literature:

4-chIoro-2-methylpyridine; With lithium diisopropyl amide;

ethyl iodide;

Reference yield:

4-chloro-1-(phenoxycarbonyl)-2-n-propyl-1,2-dihydropyridine (132410-17-4) → 4-chloro-2-propylpyridine (93856-98-5)

Guidance literature:

With o-tetrachloroquinone; acetic acid; In toluene; for 24h; Yield given; Ambient temperature;

DOI:10.1021/jo00222a050

upstream raw materials:

4-chloro-1-(phenoxycarbonyl)-2-n-propyl-1,2-dihydropyridine

4-chIoro-2-methylpyridine

ethyl iodide

4-Chloropyridine

Downstream raw materials:

2-[2-(4-chloro-pyridin-2-yl)-1-(4-methoxy-benzylsulfanyl)-butylidene]-malonic acid diethyl ester

ethyl 8-chloro-1-ethyl-2-(4-methoxybenzylsulfanyl)-4-oxo-4H-quinolizine-3-carboxylate

ethyl 8-chloro-1-ethyl-4H-quinolizin-4-one-3-carboxylate