939429-23-9Relevant academic research and scientific papers
Structure-based design and synthesis of Nω-nitro-L-arginine- containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water
Seo, Jiwon,Igarashi, Jotato,Li, Huiying,Martásek, Pavel,Roman, Linda J.,Poulos, Thomas L.,Silverman, Richard B.
, p. 2089 - 2099 (2007)
The neuronal isoform of nitric oxide synthase (nNOS), the enzyme responsible for the production of nitric oxide in the central nervous system, represents an attractive target for the treatment of various neurodegenerative disorders. X-ray crystal structur
