93957-49-4

Basic information

• Product Name: 3-(4-Fluorophenyl)-1-isopropyl-1H-indole
• Synonyms: 3-(4-Fluoro-phenyl)-1-Isopropyl-1H-Indol;3-(4- fluorinephenyl)-1- isopropyl-1H- indole;1-Isopropyl-3-(4-flrorophenyl)-indole;1-ISOPROPYL-3-(4-FLUOROPHENYL)INDOLE;1-ISOPROPYL-3-(4-FLUOROROPHENYL)-INDOLE;(4-FLUOROPHENYL)-1-ISOPROPYL-3-INDOLE;3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOLE;3-(4-FLUOROPHENYL)-1-ISOPROPYL-1H-INDOLE
• CAS NO: 93957-49-4
• Molecular Formula: C₁₇H₁₆FN
• Molecular Weight: 253.31
• EINECS: 418-790-4
• Product Categories: Indoles and derivatives;Indole;Aromatics Compounds;Aromatics;Indole Derivatives;Fluvastatine;Fluvastatin
• Mol File: 93957-49-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 96-97°C
• Boiling Point: 389.6 °C at 760 mmHg
• Flash Point: 189.4 °C
• Appearance: Off-white crystalline solid
• Density: 1.08 g/cm³
• Vapor Pressure: 6.32E-06mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Room temperature.
• BRN: 4457093
• CAS DataBase Reference: 3-(4-Fluorophenyl)-1-isopropyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Fluorophenyl)-1-isopropyl-1H-indole(93957-49-4)
• EPA Substance Registry System: 3-(4-Fluorophenyl)-1-isopropyl-1H-indole(93957-49-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-53
• Safety Statements: 26-36-61
• Hazardous Substances Data: 93957-49-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Crystalline Solid

Uses

Fluvastatin (F601250) derivative.

InChI:InChI=1/C17H16FN/c1-12(2)19-11-16(13-7-9-14(18)10-8-13)15-5-3-4-6-17(15)19/h3-12H,1-2H3

Upstream product

• 93957-51-8 1-(4-fluorophenyl)-2-(isopropyl(phenyl)amino)ethanone 
• 101125-32-0 3-(4-fluorophenyl)-1H-indole 
• 75-26-3 isopropyl bromide 
• 16885-99-7 1-isopropyl-1H-indole 
• 1038997-83-9 (4-fluorophenyl)(2,4,6-triisopropylphenyl)iodonium triflate 
• 120-72-9 indole 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 
• 768-52-5 N-Isopropylaniline 

Downstream Products

• 101125-34-2 3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carboxaldehyde 
• 93957-50-7 3-<3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl>-2(E)-propenal 
• 100-61-8 N-methylaniline 
• 129332-30-5 3-(3-(4-fluorophenyl)-1-iso propyl-1H-indol-2-yl)Acrolein 
• 1620461-86-0 1-isopropyl-3-(4'-methylbiphenyl-4-yl)-1H-indole 
• 101125-36-4 3-(4-Fluoro-phenyl)-1-isopropyl-1H-indole-7-carbaldehyde 
• 101125-35-3 3-(4-Fluoro-phenyl)-1-isopropyl-1H-indole-5-carbaldehyde 
• 956034-97-2 2-bromomethyl-3-(4-fluorophenyl)-1-isopropylindole 

Relevant articles and documents

Synthesis, crystal studies and in vivo anti-hyperlipidemic activities of indole derivatives containing fluvastatin nucleus

As a part of our efforts to prepare better analogues of fluvastatin for the treatment of hyperlipidemia, we have synthesized some indole derivatives containing a fluvastatin nucleus by methanol mediated Claisen-Schmidt aldol condensation reaction. The new

Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof

Compounds of the formula STR1 wherein one of R and Ro is STR2 and the other is primary or secondary C1-6 alkyl not containing an asymmetric carbon atom, C3-6 cycloalkyl or phenyl(CH2)m --, wherein Rs