93960-17-9Relevant academic research and scientific papers
Spiro-2-aza-alkane-3-carbonitriles, their preparation and their use
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, (2008/06/13)
The invention provides compounds of the formula I STR1 in which m is 1 to 3 and n is 1 to 4, a process for their preparation, and their use as intermediates for the manufacture of valuable medicaments, and starting products for the preparation of compound
SYNTHESYS OF UNNATURAL AMINO ACIDS: SPIRO-2-AZA-DECAN-CARBOXYLIC ACID
Teetz, V.,Gaul, H.
, p. 4483 - 4486 (2007/10/02)
Spiro-2-aza-alkan-carboxylic acids represent bulky proline analogues with increased lipophilicity.They are readily available from cyclic nitriles via alkylation with bromoacetaldehyde acetals, reduction to the corresponding amine, cyclisation to the
