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Uridine, 5-chloro-2',3'-O-(1-methylethylidene)-, 5'-(4-methylbenzenesulfonate) is a complex organic compound with the molecular formula C16H19ClN2O8S. It is a derivative of uridine, a nucleoside that plays a crucial role in RNA synthesis. The compound features a 5-chloro substitution on the uridine base, a 1-methylethylidene bridge between the 2' and 3' positions of the ribose sugar, and a 4-methylbenzenesulfonate group at the 5' position. This chemical modification may alter the properties and interactions of the uridine molecule, potentially affecting its biological activity and applications in research or therapeutics. The compound is likely to be used in specialized biochemical or pharmaceutical applications due to its unique structure.

94048-46-1

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94048-46-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 94048-46-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,0,4 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 94048-46:
(7*9)+(6*4)+(5*0)+(4*4)+(3*8)+(2*4)+(1*6)=141
141 % 10 = 1
So 94048-46-1 is a valid CAS Registry Number.

94048-46-1Relevant academic research and scientific papers

Synthesis of 6,5'-cyclo-5'-deoxyuridines by radical cyclization (nucleosides and nucleotides. L)

Ueda,Usui,Shuto,Inoue

, p. 3410 - 3416 (1984)

6,5'-Cyclo-5'-deoxyuridine, a fixed anti form of uridine, was synthetized by a radical cyclization of 5'-bromo(or iodo)-5'-deoxy-2',3'-O-isopropylidene-5-chloro(or bromo)-uridine and tri-n-butyltin hydride followed by dehydrohalogenation and deacetonation. The 5-bromo and 4-thio derivatives of the cyclouridine were also prepared and were converted to the 2',3'-cyclic phosphates. These nucleotides were hydrolyzed by pancreatic ribonuclease. The result showed that the enzyme recognizes the pyrimidine nucleotides in the anti form. 6,5'-Cyclo-5'-deoxycytidine was also synthesized by two routes.

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