94138-70-2

Usage

Uses

Used in Organic Electronic Devices:
2-(2-Benzofuryl)-5-phenyl-1,3,4-oxadiazole is used as a component in organic electronic devices for its beneficial electronic and optical characteristics, enhancing the performance and efficiency of these devices.
Used in Light-Emitting Diodes (LEDs):
In the field of optoelectronics, 2-(2-Benzofuryl)-5-phenyl-1,3,4-oxadiazole is utilized as a material in light-emitting diodes due to its strong fluorescence, contributing to improved light emission properties.
Used as a Fluorescent Probe in Biological Imaging:
2-(2-Benzofuryl)-5-phenyl-1,3,4-oxadiazole is employed as a fluorescent probe in biological imaging, capitalizing on its strong fluorescence for visualizing cellular and molecular processes within biological systems.
Used in Antitumor Applications:
2-(2-Benzofuryl)-5-phenyl-1,3,4-oxadiazole is used as a potential antitumor agent, leveraging its ability to inhibit cancer cell growth, and is under investigation for its therapeutic potential in oncology research.
Used in Research and Development:
In the field of organic chemistry, 2-(2-Benzofuryl)-5-phenyl-1,3,4-oxadiazole represents an interesting area of research, with potential applications being explored across various industries, including pharmaceuticals, materials science, and biotechnology.

Upstream product

• 825-56-9 2-phenyl-1,3,4-oxadiazole 
• 91703-34-3 2-(β,β-dibromovinyl)phenol 
• 42974-19-6 benzo[b]furan-2-carbohydrazide 
• 65-85-0 benzoic acid 

Relevant academic research and scientific papers

Highly efficient copper/palladium-catalyzed tandem Ullman reaction/arylation of azoles via C-H activation: Synthesis of benzofuranyl and indolyl azoles from 2-(gem-dibromovinyl)phenols(anilines) with azoles

In this paper, a novel and highly efficient copper/palladium-catalyzed tandem intramolecular Ullman-type C-O(N) coupling reaction of 2-(gem-dibromovinyl)phenols(anilines) followed by an intermolecular arylation of azoles through C-H activation has been developed. In the presence of CuBr with Pd(PPh3)2Cl2 used as co-catalyst, and LiO tBu as a base, the one-pot reactions of 2-(gem-dibromovinyl)phenols and 2-(gem-dibromovinyl)anilines with a variety of azoles, including oxazoles, imidazoles, thiazoles, and oxadiazoles underwent smoothly in toluene at 100 °C to generate the corresponding biheteroaryl products in high yields. A tentative mechanism of copper/palladium-catalyzed tandem reaction was described.

One-pot synthesis of benzofused heteroaryl azoles via tandem C-heteroatom coupling/C-H activation of azoles

The Cu(i) or Pd(ii)-catalyzed cross-couplings of gem-dihaloolefins with azoles via tandem C-heteroatom coupling/C-H activation for the preparation of benzofused heteroaryl azoles have been developed.

Utilization of 2-benzo[b]furan carboxylic acid hydrazide in the synthesis of 1,3,4-oxadiazole derivatives

(Chemical Equation Presented) In this study, the synthesis of series of 2-benzo[b]furan-substituted 1,3,4-oxadiazole derivatives using readily available 2-benzo[b]furan carboxylic acid hydrazide as starting material has been investigated.