94163-98-1

Basic information

• Product Name: 1-benzyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
• Synonyms: 1-benzyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
• CAS NO: 94163-98-1
• Molecular Formula: C₁₈H₁₉N*ClH
• Molecular Weight: 285.8111
• Mol File: 94163-98-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride(94163-98-1)
• EPA Substance Registry System: 1-benzyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride(94163-98-1)

Safety Data

• Hazardous Substances Data: 94163-98-1(Hazardous Substances Data)

Usage

Common uses

Inducing Parkinson's disease-like symptoms in animal models for scientific research

Functionality

Neurotoxin that selectively destroys dopaminergic neurons in the brain, leading to motor deficits and behavioral changes characteristic of Parkinson's disease

Upstream product

• 108-86-1 bromobenzene 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 38025-45-5 1-benzyl-4-phenyl-1,2,3,6-tetrahydro-pyridine 
• 63843-83-4 1-benzyl-4-hydroxy-4-phenylpiperidine 

Downstream Products

• 10272-49-8 4-phenylpiperidine hydrochloride 

Relevant articles and documents

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6- tetrahydropyridines as 5-HT2C agonists

A series of substituted 4-arylpiperidines and a smaller family of 4-aryl-1,2,3,6-tetrahydropyridines were synthesized and their biological activity at the 5-HT2C receptor studied to determine whether either series showed noteworthy agonist activity. Structure-activity relationships were developed from the performed receptor binding assays and functional studies, and the results of the analysis are presented herein.