941702-75-6

Upstream product

• 30379-58-9 benzyl glycolate 
• 5538-51-2 O-acetylsalicyloyl chloride 
• 140-18-1 Benzyl chloroacetate 
• 50-78-2 aspirin 
• 100-39-0 benzyl bromide 

Downstream Products

• 677716-61-9 2-acetoxybenzoic acid carboxymethyl ester 
• 1240261-39-5 2-acetoxybenzoic acid 4-bromobutoxycarbonylmethyl ester 
• 1240261-40-8 2-acetoxy-benzoic acid 4-nitrooxy-butoxy carbonyl methyl ester 
• 1609647-77-9 C₂₁H₂₈O₁₀ 
• 941702-69-8 C₁₅H₁₇N₃O₁₀ 
• 941702-68-7 C₁₆H₂₀N₂O₈ 
• 941702-67-6 C₁₅H₁₈N₂O₈ 
• 941702-66-5 C₁₄H₁₆N₂O₈ 
• 941702-76-7 C₁₁H₉ClO₅ 

Relevant academic research and scientific papers

ABSORBABLE BRANCHED POLYESTERS AND POLYURETHANES

The present invention relates to the discovery of a new class of hydrolysable isocyanates, hydrolysable branched polyols and branched absorbable polyesters and polyurethanes prepared therefrom. The resultant absorbable polymers are useful for drug delivery, stents, highly porous foam, reticulated foam, tissue engineering, tissue adhesives, adhesion prevention, bone wax formulations, medical device coatings, surface modifying agents and other implantable medical devices. In addition, these absorbable polymers can have a controlled hydrolytic degradation profile.

Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers

The present invention provides NO and, optionally, drug releasing macromers and oligomers wherein the drug molecule and NO releasing moiety are linked an absorbable macromer or oligomeric chain susceptible to hydrolytic degradation and wherein the macrome

Evaluation of nitrate-substituted pseudocholine esters of aspirin as potential nitro-aspirins

Herein we explore some designs for nitro-aspirins, compounds potentially capable of releasing both aspirin and nitric oxide in vivo. A series of nitrate-bearing alkyl esters of aspirin were prepared based on the choline ester template preferred by human plasma butyrylcholinesterase. The degradation kinetics of the compounds were followed in human plasma solution. All compounds underwent hydrolysis rapidly (t1/2 ～ 1 min) but generating exclusively the corresponding nitro-salicylate. The one exception, an N-propyl, N-nitroxyethyl aminoethanol ester produced 9.2% aspirin in molar terms indicating that the nitro-aspirin objective is probably achievable if due cognisance can be paid to the demands of the activating enzyme. Even at this low level of aspirin release, this compound is the most successful nitro-aspirin reported to date in the key human plasma model.