87007-52-1Relevant articles and documents
Rapid and efficient syntheses of phosphorylated dinucleotides
Ferris,Peyser
, p. 1087 - 1111 (2007/10/02)
Nine or ten-step solution phase syntheses of the dimers dpApA, dApAp, dpTpT and dTpTp in 0.1-0.5 g amounts, in overall yields of 49%, 45%, 32%, and 20% respectively, are described. The synthetic intermediates were characterized by 1H and 3
A Building Block for the Sequence-Specific Introduction of Cis-Syn Thymine Dimers into Oligonucleotides. Solid-Phase Synthesis of TpTpTpT
Taylor, John-Stephen,Brockie, Ian R.,O'Day, Christine L.
, p. 6735 - 6742 (2007/10/02)
We report the synthesis of a synthetic intermediate for the sequemce specific incorporation of the cis-syn thymine dimer into oligonucleotides via phosphoramidite-based solid-phase DNA synthesis technology.The required phosphoramidite 1a was obtained in f